Cytokines of the IL-17 family in psoriasis

Felix Lauffer; Kilian Eyerich; Wolf Henning Boehncke; Khusru Asadullah; Stefan Beissert; Kamran Ghoreschi; Michael P. Schön

doi:10.1111/ddg.14124

Cytokines of the IL-17 family in psoriasis

Felix Lauffer, Kilian Eyerich, Wolf Henning Boehncke, Khusru Asadullah, Stefan Beissert, Kamran Ghoreschi, Michael P. Schön

Research output: Contribution to journal › Review article › peer-review

32 Scopus citations

Abstract

Various immune cells and their messenger substances influence the development of psoriasis. Cytokines of the IL-17 family are of particular importance. In addition to IL-17A, which plays a central role in the pathogenesis of psoriasis, other subtypes of the IL-17 family also have a proinflammatory effect. This review provides an up-to-date overview of the immunopathogenesis of psoriasis with regard to the six IL-17 subtypes, in particular their physiological and pathogenic properties, as well as their significance for psoriasis therapy.

Original language	English
Pages (from-to)	675-681
Number of pages	7
Journal	JDDG - Journal of the German Society of Dermatology
Volume	18
Issue number	7
DOIs	https://doi.org/10.1111/ddg.14124
State	Published - 1 Jul 2020
Externally published	Yes

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title = "Cytokines of the IL-17 family in psoriasis",

abstract = "Various immune cells and their messenger substances influence the development of psoriasis. Cytokines of the IL-17 family are of particular importance. In addition to IL-17A, which plays a central role in the pathogenesis of psoriasis, other subtypes of the IL-17 family also have a proinflammatory effect. This review provides an up-to-date overview of the immunopathogenesis of psoriasis with regard to the six IL-17 subtypes, in particular their physiological and pathogenic properties, as well as their significance for psoriasis therapy.",

author = "Felix Lauffer and Kilian Eyerich and Boehncke, {Wolf Henning} and Khusru Asadullah and Stefan Beissert and Kamran Ghoreschi and Sch{\"o}n, {Michael P.}",

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AU - Lauffer, Felix

AU - Eyerich, Kilian

AU - Boehncke, Wolf Henning

AU - Asadullah, Khusru

AU - Beissert, Stefan

AU - Ghoreschi, Kamran

AU - Schön, Michael P.

PY - 2020/7/1

Y1 - 2020/7/1

N2 - Various immune cells and their messenger substances influence the development of psoriasis. Cytokines of the IL-17 family are of particular importance. In addition to IL-17A, which plays a central role in the pathogenesis of psoriasis, other subtypes of the IL-17 family also have a proinflammatory effect. This review provides an up-to-date overview of the immunopathogenesis of psoriasis with regard to the six IL-17 subtypes, in particular their physiological and pathogenic properties, as well as their significance for psoriasis therapy.

AB - Various immune cells and their messenger substances influence the development of psoriasis. Cytokines of the IL-17 family are of particular importance. In addition to IL-17A, which plays a central role in the pathogenesis of psoriasis, other subtypes of the IL-17 family also have a proinflammatory effect. This review provides an up-to-date overview of the immunopathogenesis of psoriasis with regard to the six IL-17 subtypes, in particular their physiological and pathogenic properties, as well as their significance for psoriasis therapy.

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M3 - Review article

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JF - JDDG - Journal of the German Society of Dermatology

IS - 7

ER -

Cytokines of the IL-17 family in psoriasis

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