Cryo-EM structure of the ClpXP protein degradation machinery

Keyphrases

• AAA+ 20%
• AAA+ Chaperone 20%
• Activation Mechanism 20%
• ATP Binding 20%
• ATP Hydrolysis 20%
• Binding Interface 20%
• ClpP 100%
• ClpX 80%
• ClpXP 100%
• Complex Modes 20%
• Cryo-EM Structure 100%
• Heptamer 20%
• Hexamer 60%
• Listeria Monocytogenes 20%
• Mitochondria 20%
• Mode of Action 20%
• Peptidase 20%
• Pharmacological Applications 20%
• Protease Complex 20%
• Protein Degradation 100%
• Structural Framework 20%
• Symmetry Mismatch 20%
• Targeted Protein Degradation 20%
• Translocated 20%
• Two-component 20%

Biochemistry, Genetics and Molecular Biology

• AAA+ 100%
• Adenosine Triphosphate 50%
• Cryoelectron Microscopy 100%
• Crystal Structure 50%
• Enzymatic Hydrolysis 50%
• Listeria monocytogenes 50%
• Mitochondrion 50%
• Peptidase 50%
• Proteasome 50%
• Protein Catabolism 100%