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COVID-19 and beyond: a call for action and audacious solidarity to all the citizens and nations, it is humanity’s fight

  • Charles Auffray
  • , Rudi Balling
  • , Niklas Blomberg
  • , Myrna C. Bonaldo
  • , Bertrand Boutron
  • , Samir Brahmachari
  • , Christian Bréchot
  • , Alfredo Cesario
  • , Sai Juan Chen
  • , Karine Clément
  • , Daria Danilenko
  • , Alberto Di Meglio
  • , Andrea Gelemanović
  • , Carole Goble
  • , Takashi Gojobori
  • , Jason D. Goldman
  • , Michel Goldman
  • , Yi Ke Guo
  • , James Heath
  • , Leroy Hood
  • Peter Hunter, Li Jin, Hiroaki Kitano, Bartha Knoppers, Doron Lancet, Catherine Larue, Mark Lathrop, Martine Laville, Ariel B. Lindner, Antoine Magnan, Andres Metspalu, Edgar Morin, Lisa F.P. Ng, Laurent Nicod, Denis Noble, Laurent Nottale, Helga Nowotny, Theresa Ochoa, Iruka N. Okeke, Tolu Oni, Peter Openshaw, Mehmet Oztürk, Susanna Palkonen, Janusz T. Paweska, Christophe Pison, Mihael H. Polymeropoulos, Christian Pristipino, Ulrike Protzer, Josep Roca, Damjana Rozman, Marc Santolini, Ferran Sanz, Giovanni Scambia, Eran Segal, Ismail Serageldin, Marcelo Bento Soares, Peter Sterk, Sumio Sugano, Giulio Superti-Furga, David Supple, Jesper Tegner, Mathias Uhlen, Andrea Urbani, Alfonso Valencia, Vincenzo Valentini, Sylvie van der Werf, Manlio Vinciguerra, Olaf Wolkenhauer, Emiel Wouters
  • EISBM
  • University of Luxembourg
  • ELIXIR Hub
  • Oswaldo Cruz Foundation
  • Institute of Genomics and Integrative Biology India
  • University of South Florida, Tampa
  • Università Cattolica del Sacro Cuore
  • Italian Association for Systems Medicine and Healthcare - ASSIMSS
  • Jiao Tong University School of Medicine
  • AP-HP
  • Smorodintsev Research Institute of Influenza
  • European Organization for Nuclear Research
  • Mediterranean Institute for Life Sciences
  • University of Manchester
  • King Abdullah University of Science and Technology
  • National Institute of Genetics Mishima
  • Providence St. Joseph Health
  • Université Libre de Bruxelles
  • Imperial College London
  • Hong Kong Baptist University
  • Institute for Systems Biology
  • Auckland Bioengineering Institute
  • Fudan University
  • Systems Biology Institute
  • Okinawa Institute of Science and Technology Graduate University
  • McGill University Montreal
  • Weizmann Institute of Science Israel
  • Integrated BioBank of Luxembourg
  • Lyon-Sud University Hospital
  • Univ-Paris Diderot Sorbonne Paris-Cité
  • l'institut du thorax
  • University of Tartu
  • Association pour la Pensée Complexe
  • A*STAR
  • Centre Hospitalier Universitaire Vaudois
  • University of Oxford Medical Sciences Division
  • Paris-Meudon Observatory
  • Vienna Science and Technology Fund
  • Universidad Peruana Cayetano Heredia, Instituto de Medicina Tropical Alexander von Humboldt
  • University of Ibadan
  • University of Cambridge School of Clinical Medicine
  • University of Cape Town
  • National Heart and Lung Institute
  • Dokuz Eylul University Health Campus
  • Patient Access Partnership
  • National Health Laboratory Service
  • Grenoble-Alps University Albert Michallon Hospital
  • Vanda Pharmaceuticals
  • San Filippo Neri Hospital
  • Hospital Clinic Barcelona
  • University of Ljubljana
  • Pompeu Fabra University (UPF)
  • Library of Alexandria
  • University of Illinois College of Medicine
  • Amsterdam University Medical Centers
  • University of Tokyo
  • Chiba-U
  • Medical University of Vienna
  • Asthma-UK
  • Karolinska Institutet at Karolinska University Hospital
  • Center for Autonomous Systems
  • Barcelona Supercomputing Center
  • Institut Pasteur, Paris
  • St. Anne's University Hospital and CEITEC
  • University of Rostock
  • University of Maastricht
  • Ludwig-Boltzmann Institute for Clinical Forensic Imaging

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Background: Severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) belongs to a subgroup of coronaviruses rampant in bats for centuries. It caused the coronavirus disease 2019 (COVID-19) pandemic. Most patients recover, but a minority of severe cases experience acute respiratory distress or an inflammatory storm devastating many organs that can lead to patient death. The spread of SARS-CoV-2 was facilitated by the increasing intensity of air travel, urban congestion and human contact during the past decades. Until therapies and vaccines are available, tests for virus exposure, confinement and distancing measures have helped curb the pandemic. Vision: The COVID-19 pandemic calls for safeguards and remediation measures through a systemic response. Self-organizing initiatives by scientists and citizens are developing an advanced collective intelligence response to the coronavirus crisis. Their integration forms Olympiads of Solidarity and Health. Their ability to optimize our response to COVID-19 could serve as a model to trigger a global metamorphosis of our societies with far-reaching consequences for attacking fundamental challenges facing humanity in the 21st century. Mission: For COVID-19 and these other challenges, there is no alternative but action. Meeting in Paris in 2003, we set out to "rethink research to understand life and improve health." We have formed an international coalition of academia and industry ecosystems taking a systems medicine approach to understanding COVID-19 by thoroughly characterizing viruses, patients and populations during the pandemic, using openly shared tools. All results will be publicly available with no initial claims for intellectual property rights. This World Alliance for Health and Wellbeing will catalyze the creation of medical and health products such as diagnostic tests, drugs and vaccines that become common goods accessible to all, while seeking further alliances with civil society to bridge with socio-ecological and technological approaches that characterise urban systems, for a collective response to future health emergencies.

Original languageEnglish
Pages (from-to)1-18
Number of pages18
JournalF1000Research
Volume9
DOIs
StatePublished - 2021

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being
  2. SDG 11 - Sustainable Cities and Communities
    SDG 11 Sustainable Cities and Communities

Keywords

  • COVID-19
  • Coalition
  • Coronavirus
  • Pandemic
  • SARS-CoV-2
  • Solidarity
  • Systemic crisis
  • Systemic response

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