@article{52661c5760fb4f6591cd1692e47c352f,
title = "COVID-19 and beyond: a call for action and audacious solidarity to all the citizens and nations, it is humanity{\textquoteright}s fight",
abstract = "Background: Severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) belongs to a subgroup of coronaviruses rampant in bats for centuries. It caused the coronavirus disease 2019 (COVID-19) pandemic. Most patients recover, but a minority of severe cases experience acute respiratory distress or an inflammatory storm devastating many organs that can lead to patient death. The spread of SARS-CoV-2 was facilitated by the increasing intensity of air travel, urban congestion and human contact during the past decades. Until therapies and vaccines are available, tests for virus exposure, confinement and distancing measures have helped curb the pandemic. Vision: The COVID-19 pandemic calls for safeguards and remediation measures through a systemic response. Self-organizing initiatives by scientists and citizens are developing an advanced collective intelligence response to the coronavirus crisis. Their integration forms Olympiads of Solidarity and Health. Their ability to optimize our response to COVID-19 could serve as a model to trigger a global metamorphosis of our societies with far-reaching consequences for attacking fundamental challenges facing humanity in the 21st century. Mission: For COVID-19 and these other challenges, there is no alternative but action. Meeting in Paris in 2003, we set out to {"}rethink research to understand life and improve health.{"} We have formed an international coalition of academia and industry ecosystems taking a systems medicine approach to understanding COVID-19 by thoroughly characterizing viruses, patients and populations during the pandemic, using openly shared tools. All results will be publicly available with no initial claims for intellectual property rights. This World Alliance for Health and Wellbeing will catalyze the creation of medical and health products such as diagnostic tests, drugs and vaccines that become common goods accessible to all, while seeking further alliances with civil society to bridge with socio-ecological and technological approaches that characterise urban systems, for a collective response to future health emergencies.",
keywords = "COVID-19, Coalition, Coronavirus, Pandemic, SARS-CoV-2, Solidarity, Systemic crisis, Systemic response",
author = "Charles Auffray and Rudi Balling and Niklas Blomberg and Bonaldo, {Myrna C.} and Bertrand Boutron and Samir Brahmachari and Christian Br{\'e}chot and Alfredo Cesario and Chen, {Sai Juan} and Karine Cl{\'e}ment and Daria Danilenko and Meglio, {Alberto Di} and Andrea Gelemanovi{\'c} and Carole Goble and Takashi Gojobori and Goldman, {Jason D.} and Michel Goldman and Guo, {Yi Ke} and James Heath and Leroy Hood and Peter Hunter and Li Jin and Hiroaki Kitano and Bartha Knoppers and Doron Lancet and Catherine Larue and Mark Lathrop and Martine Laville and Lindner, {Ariel B.} and Antoine Magnan and Andres Metspalu and Edgar Morin and Ng, {Lisa F.P.} and Laurent Nicod and Denis Noble and Laurent Nottale and Helga Nowotny and Theresa Ochoa and Okeke, {Iruka N.} and Tolu Oni and Peter Openshaw and Mehmet Ozt{\"u}rk and Susanna Palkonen and Paweska, {Janusz T.} and Christophe Pison and Polymeropoulos, {Mihael H.} and Christian Pristipino and Ulrike Protzer and Josep Roca and Damjana Rozman and Marc Santolini and Ferran Sanz and Giovanni Scambia and Eran Segal and Ismail Serageldin and Soares, {Marcelo Bento} and Peter Sterk and Sumio Sugano and Giulio Superti-Furga and David Supple and Jesper Tegner and Mathias Uhlen and Andrea Urbani and Alfonso Valencia and Vincenzo Valentini and {van der Werf}, Sylvie and Manlio Vinciguerra and Olaf Wolkenhauer and Emiel Wouters",
note = "Funding Information: Grant information: This work was supported during its preparation phases by the State Key Laboratory of Medical Genomics, Overseas Expertise Introduction Project for Discipline Innovation [111 Project, B17029] to SJC, LH, CA; European Union grants CASyM [FP7-n°305033] to CA, RB, JR, DR, DS, JT, OW; eTRIKS (IMI-1-n°115446) to CA, RB, YG; PREPARE [FP7-n°602525] to CA, PO, SV; and initial funds in support of the deep phenotyping clinical study from philanthropic donors, Gilead, Merck and Novartis to JG, JH, LH; the Ricerca Corrente Program by the Italian Ministry of Health to AC, CPr, GS, AU, VV; the National Megaprojects of China for Infectious Diseases [2017ZX10103009-001, 2018ZX10305409-001-005], Double First-class projects from the Ministry of Education to the National Research Center for Translational Medicine Shanghai to SJC; Shanghai Municipal Science and Technology Major Project [2017SHZDZX01] to LJ. Funding Information: This work was supported during its preparation phases by the State Key Laboratory of Medical Genomics, Overseas Expertise Introduction Project for Discipline Innovation [111 Project, B17029] to SJC, LH, CA; European Union grants CASyM [FP7-n?305033] to CA, RB, JR, DR, DS, JT, OW; eTRIKS (IMI-1-n?115446) to CA, RB, YG; PREPARE [FP7-n?602525] to CA, PO, SV; and initial funds in support of the deep phenotyping clinical study from philanthropic donors, Gilead, Merck and Novartis to JG, JH, LH; the Ricerca Corrente Program by the Italian Ministry of Health to AC, CPr, GS, AU, VV; the National Megaprojects of China for Infectious Diseases [2017ZX10103009-001, 2018ZX10305409-001-005], Double First-class projects from the Ministry of Education to the National Research Center for Translational Medicine Shanghai to SJC; Shanghai Municipal Science and Technology Major Project [2017SHZDZX01] to LJ. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Publisher Copyright: {\textcopyright} 2020. Auffray C et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited",
year = "2021",
doi = "10.12688/F1000RESEARCH.26098.1",
language = "English",
volume = "9",
pages = "1--18",
journal = "F1000Research",
issn = "2046-1402",
publisher = "F1000 Research Ltd.",
}
