CO₂/HCO₃ ⁻ perturbations of simulated large scale gradients in a scale-down device cause fast transcriptional responses in Corynebacterium glutamicum

Keyphrases

• Downscaling 100%
• Residence Time 100%
• Partial Pressure of CO2 (pCO2) 100%
• Transcriptional Response 100%
• Corynebacterium Glutamicum 100%
• HCO3 100%
• Large-scale Gradients 100%
• Bioreactor 33%
• Control Condition 33%
• Process Performance 33%
• Large-scale Bioreactor 33%
• Product Formation 33%
• Fermentation 33%
• Differentially Expressed Genes 33%
• Metabolic Response 33%
• Phenomenological Analysis 33%
• Lysine Production 33%
• Dissolved Oxygen 33%
• Transcriptional Analysis 33%
• Cellular Metabolism 33%
• Cascade Bioreactors 33%
• Bioreactor Inhomogeneity 33%
• Model Strain 33%
• Substrate pH 33%
• Changes in Gene Expression 33%
• High Flexibility 33%
• Bioreactor System 33%
• Typical Scenario 33%

Chemical Engineering

• Carbon Dioxide 100%
• Biochemical Reactor 100%
• Dissolved Oxygen 33%