Abstract
Pyruvate as a key metabolite of the central metabolism in bacteria is also a precursor for several biotechnologically relevant compounds. Therefore, efforts have been made to tailor the metabolism of the industrially relevant Corynebacterium glutamicum for optimal pyruvate availability and an optimal flux towards pyruvate-derived products. Here we summarize the recent achievements on metabolic engineering of C. glutamicum for production of pyruvate, L-valine, 2-ketoisovalerate and isobutanol.
| Translated title of the contribution | Corynebacterium glutamicum as producer of pyruvate-derived products |
|---|---|
| Original language | English |
| Pages (from-to) | 696-699 |
| Number of pages | 4 |
| Journal | BioSpektrum |
| Volume | 20 |
| Issue number | 6 |
| DOIs | |
| State | Published - 30 Sep 2014 |
| Externally published | Yes |