TY - JOUR
T1 - Corneal collagen crosslinking in post-LASIK keratectasia
AU - Salgado, Josefina P.
AU - Khoramnia, R.
AU - Lohmann, C. P.
AU - Winkler Von Mohrenfels, C.
PY - 2011/4
Y1 - 2011/4
N2 - Background/aims: To evaluate the effect of corneal collagen crosslinking with riboflavin and UV-A as a treatment option for postlaser in situ keratomileusis keratectasia. Methods: Crosslinking was carried out in 22 eyes of 15 patients with iatrogenic keratectasia. Follow-up, according to a standardised protocol (uncorrected visual acuity (UCVA), best-corrected visual acuity (BCVA), slit-lamp examination, pachymetry and topography), was performed preoperatively 1, 3, 6 and 12 months after crosslinking. Results: The mean BCVA was 0.19 (SD±0.21) logMAR preoperatively, 0.25 (SD±0.17) 1 month, 0.20 (SD±0.20) 3 months, 0.18 (SD±0.21) 6 months and 0.15 (SD±0.14) 12 months postoperatively (statistically significant postop1-postop6, p=0.0335). The maximum k-readings were 44.12 (SD±3.97) preoperatively, 46.23 (SD±4.14) 1 month, 43.88 (SD±4.25) 3 months, 45.06 (SD±5.07) 6 months and 44.43 (SD±4.06) 12 months postoperatively (statistically significant preop-postop1, p=0.0281). Conclusion: Crosslinking in patients with iatrogenic keratectasia stabilised the UCVA and BCVA as well as the maximum k-readings in our cohort. It seems to be a safe and promising procedure to stabilise the refraction and the corneal topography, and thus to stop the progression of visual loss, thereby avoiding or delaying disease progression and keratoplasty.
AB - Background/aims: To evaluate the effect of corneal collagen crosslinking with riboflavin and UV-A as a treatment option for postlaser in situ keratomileusis keratectasia. Methods: Crosslinking was carried out in 22 eyes of 15 patients with iatrogenic keratectasia. Follow-up, according to a standardised protocol (uncorrected visual acuity (UCVA), best-corrected visual acuity (BCVA), slit-lamp examination, pachymetry and topography), was performed preoperatively 1, 3, 6 and 12 months after crosslinking. Results: The mean BCVA was 0.19 (SD±0.21) logMAR preoperatively, 0.25 (SD±0.17) 1 month, 0.20 (SD±0.20) 3 months, 0.18 (SD±0.21) 6 months and 0.15 (SD±0.14) 12 months postoperatively (statistically significant postop1-postop6, p=0.0335). The maximum k-readings were 44.12 (SD±3.97) preoperatively, 46.23 (SD±4.14) 1 month, 43.88 (SD±4.25) 3 months, 45.06 (SD±5.07) 6 months and 44.43 (SD±4.06) 12 months postoperatively (statistically significant preop-postop1, p=0.0281). Conclusion: Crosslinking in patients with iatrogenic keratectasia stabilised the UCVA and BCVA as well as the maximum k-readings in our cohort. It seems to be a safe and promising procedure to stabilise the refraction and the corneal topography, and thus to stop the progression of visual loss, thereby avoiding or delaying disease progression and keratoplasty.
UR - http://www.scopus.com/inward/record.url?scp=79952929429&partnerID=8YFLogxK
U2 - 10.1136/bjo.2010.179424
DO - 10.1136/bjo.2010.179424
M3 - Article
C2 - 20679077
AN - SCOPUS:79952929429
SN - 0007-1161
VL - 95
SP - 493
EP - 497
JO - British Journal of Ophthalmology
JF - British Journal of Ophthalmology
IS - 4
ER -