Copper-catalyzed enantioselective hydrogenation of ketones

Kathrin Junge, Bianca Wendt, Daniele Addis, Shaolin Zhou, Shoubhik Das, Steffen Fleischer, Matthias Beller

Research output: Contribution to journalArticlepeer-review

71 Scopus citations

Abstract

Not so precious! The combination of copper acetate and chiral monodentate ligands allows the enantioselective hydrogenation of carbonyl compounds to take place in good to high yields with moderate to good enantioselectivities (see scheme).

Original languageEnglish
Pages (from-to)101-105
Number of pages5
JournalChemistry - A European Journal
Volume17
Issue number1
DOIs
StatePublished - 3 Jan 2011
Externally publishedYes

Keywords

  • P ligands
  • copper
  • homogeneous catalysis
  • hydrogenation
  • ketones

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