Convenient synthesis of 68Ga-labeled gadolinium(III) complexes: Towards bimodal responsive probes for functional imaging with PET/MRI

Johannes Notni; Petr Hermann; Isabel Dregely; Hans Jürgen Wester

doi:10.1002/chem.201302751

Convenient synthesis of ⁶⁸Ga-labeled gadolinium(III) complexes: Towards bimodal responsive probes for functional imaging with PET/MRI

Johannes Notni, Petr Hermann, Isabel Dregely, Hans Jürgen Wester

Default

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Abstract

A killer application? Recently, fully integrated full-body positron-emission tomography (PET) and magnetic-resonance imaging (MRI) scanners were brought to market, allowing simultaneous recording of complementary 3D data sets. By using bimodal PET/MRI probes (see figure), in vivo 3D mapping of various parameters with medical relevance could become feasible.

Original language	English
Pages (from-to)	12602-12606
Number of pages	5
Journal	Chemistry - A European Journal
Volume	19
Issue number	38
DOIs	https://doi.org/10.1002/chem.201302751
State	Published - 16 Sep 2013

Keywords

contrast agents
gallium-68
macrocyclic ligands
magnetic resonance imaging
positron emission tomography
radiopharmaceuticals

Access to Document

10.1002/chem.201302751

Cite this

@article{5867595d2dc644d589818da479d7d9eb,

title = "Convenient synthesis of 68Ga-labeled gadolinium(III) complexes: Towards bimodal responsive probes for functional imaging with PET/MRI",

abstract = "A killer application? Recently, fully integrated full-body positron-emission tomography (PET) and magnetic-resonance imaging (MRI) scanners were brought to market, allowing simultaneous recording of complementary 3D data sets. By using bimodal PET/MRI probes (see figure), in vivo 3D mapping of various parameters with medical relevance could become feasible.",

keywords = "contrast agents, gallium-68, macrocyclic ligands, magnetic resonance imaging, positron emission tomography, radiopharmaceuticals",

author = "Johannes Notni and Petr Hermann and Isabel Dregely and Wester, {Hans J{\"u}rgen}",

year = "2013",

month = sep,

day = "16",

doi = "10.1002/chem.201302751",

language = "English",

volume = "19",

pages = "12602--12606",

journal = "Chemistry - A European Journal",

issn = "0947-6539",

publisher = "Wiley-VCH Verlag",

number = "38",

}

TY - JOUR

T1 - Convenient synthesis of 68Ga-labeled gadolinium(III) complexes

T2 - Towards bimodal responsive probes for functional imaging with PET/MRI

AU - Notni, Johannes

AU - Hermann, Petr

AU - Dregely, Isabel

AU - Wester, Hans Jürgen

PY - 2013/9/16

Y1 - 2013/9/16

N2 - A killer application? Recently, fully integrated full-body positron-emission tomography (PET) and magnetic-resonance imaging (MRI) scanners were brought to market, allowing simultaneous recording of complementary 3D data sets. By using bimodal PET/MRI probes (see figure), in vivo 3D mapping of various parameters with medical relevance could become feasible.

AB - A killer application? Recently, fully integrated full-body positron-emission tomography (PET) and magnetic-resonance imaging (MRI) scanners were brought to market, allowing simultaneous recording of complementary 3D data sets. By using bimodal PET/MRI probes (see figure), in vivo 3D mapping of various parameters with medical relevance could become feasible.

KW - contrast agents

KW - gallium-68

KW - macrocyclic ligands

KW - magnetic resonance imaging

KW - positron emission tomography

KW - radiopharmaceuticals

UR - http://www.scopus.com/inward/record.url?scp=84884286286&partnerID=8YFLogxK

U2 - 10.1002/chem.201302751

DO - 10.1002/chem.201302751

M3 - Article

C2 - 24175335

AN - SCOPUS:84884286286

SN - 0947-6539

VL - 19

SP - 12602

EP - 12606

JO - Chemistry - A European Journal

JF - Chemistry - A European Journal

IS - 38

ER -

Convenient synthesis of ⁶⁸Ga-labeled gadolinium(III) complexes: Towards bimodal responsive probes for functional imaging with PET/MRI

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this