Controlling DNA polymerization with a switchable aptamer

Eike Friedrichs, Friedrich C. Simmel

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

Controllable biochemical reactions. DNA polymerization by Taq polymerase can be controlled by switching an aptamer for Taq Pol between a binding and a nonbinding form. (Figure Presented).

Original languageEnglish
Pages (from-to)1662-1666
Number of pages5
JournalChemBioChem
Volume8
Issue number14
DOIs
StatePublished - 24 Sep 2007
Externally publishedYes

Keywords

  • Aptamers
  • Molecular devices
  • Oligonucleotides
  • Switches
  • Taq polymerase

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