Controlling Chirality across Length Scales using DNA

Alessandro Cecconello, Friedrich C. Simmel

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


Nano-objects with chiral properties attract growing interest due to their relevance for a wide variety of technological applications. For example, chiral nano-objects may be used in characterization platforms that involve chiral molecular recognition of proteins or in the fabrication of nanomechanical devices such as screw-gears or nanoswimmers. Spatial ordering of emitters of circularly polarized light might greatly benefit from the utilization of chiral shapes. Tools developed in DNA nanotechnology now allow precise tailoring of the chiral properties of molecules and materials at various length scales. Among others, they have already been applied to control the handedness of helical shapes (configurational chirality) or the chiral positioning of different-sized nanoparticles at the vertices of tetrahedra (compositional chirality). This work covers some of the key advances and recent developments in the field of chiral DNA nanoarchitectures and discusses their future perspectives and potential applications.

Original languageEnglish
Article number1805419
Issue number26
StatePublished - 26 Jun 2019


  • DNA nanotechnology
  • asymmetric catalysis
  • circularly polarized light
  • molecular recognition
  • nucleic acids


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