Continuous wave laser diodes enable fast optoacoustic imaging

Antonios Stylogiannis; Ludwig Prade; Andreas Buehler; Juan Aguirre; George Sergiadis; Vasilis Ntziachristos

doi:10.1016/j.pacs.2017.12.002

Continuous wave laser diodes enable fast optoacoustic imaging

Antonios Stylogiannis, Ludwig Prade, Andreas Buehler, Juan Aguirre, George Sergiadis, Vasilis Ntziachristos

Chair of Biological Imaging

Research output: Contribution to journal › Article › peer-review

52 Scopus citations

Abstract

Pulsed laser diodes may offer a smaller, less expensive alternative to conventional optoacoustic laser sources; however they do not provide pulse rates faster than a few tens of kHz and emit at wavelengths only within the near-infrared region. We investigated whether continuous wave (CW) laser diodes, which are available in visible and near-infrared regions, can be good optoacoustic light sources when overdriven with a peak current >40-fold higher than the CW absolute maximum. We found that overdriven CW diodes provided ∼10 ns pulses of ∼200 nJ/pulse and repetition rates higher than 600 kHz without being damaged, outperforming many pulsed laser diodes. Using this system, we obtained images of phantoms and mouse ear and human arm in vivo, confirming their use in optoacoustic imaging and sensing.

Original language	English
Pages (from-to)	31-38
Number of pages	8
Journal	Photoacoustics
Volume	9
DOIs	https://doi.org/10.1016/j.pacs.2017.12.002
State	Published - Mar 2018

Keywords

Current drivers
Light sources
Light-emitting diodes
Near-infrared
Photoacoustic
Visible

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10.1016/j.pacs.2017.12.002

Cite this

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title = "Continuous wave laser diodes enable fast optoacoustic imaging",

abstract = "Pulsed laser diodes may offer a smaller, less expensive alternative to conventional optoacoustic laser sources; however they do not provide pulse rates faster than a few tens of kHz and emit at wavelengths only within the near-infrared region. We investigated whether continuous wave (CW) laser diodes, which are available in visible and near-infrared regions, can be good optoacoustic light sources when overdriven with a peak current >40-fold higher than the CW absolute maximum. We found that overdriven CW diodes provided ∼10 ns pulses of ∼200 nJ/pulse and repetition rates higher than 600 kHz without being damaged, outperforming many pulsed laser diodes. Using this system, we obtained images of phantoms and mouse ear and human arm in vivo, confirming their use in optoacoustic imaging and sensing.",

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author = "Antonios Stylogiannis and Ludwig Prade and Andreas Buehler and Juan Aguirre and George Sergiadis and Vasilis Ntziachristos",

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AU - Stylogiannis, Antonios

AU - Prade, Ludwig

AU - Buehler, Andreas

AU - Aguirre, Juan

AU - Sergiadis, George

AU - Ntziachristos, Vasilis

PY - 2018/3

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Continuous wave laser diodes enable fast optoacoustic imaging

Abstract

Keywords

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