TY - GEN
T1 - Construction of a neonatal cortical surface atlas using multimodal surface matching
AU - Bozek, Jelena
AU - Fitzgibbon, Sean
AU - Wright, Robert
AU - Rueckert, Daniel
AU - Jenkinson, Mark
AU - Robinson, Emma C.
N1 - Publisher Copyright:
© 2016 IEEE.
PY - 2016/6/15
Y1 - 2016/6/15
N2 - In this paper we propose a method for constructing a spatiotemporal cortical surface atlas of neonatal brains aged between 38 and 42 weeks of gestation at the time of scan. The method is based on a spherical registration approach: multimodal surface matching (MSM) registration, where cortical folding patterns were used to drive alignment. Cortical surfaces from 44 subjects were projected onto spheres and grouped into 5 weeks, with all surfaces within each group co-registered using pairwise MSM registration in order to avoid bias in the atlas towards any of the subjects. Finally, warps were projected to the anatomical surfaces to allow averaging of white matter surfaces, and folding metrics, in the template space. Our approach improves the sharpness of the templates from what can be achieved using affine alignment alone.
AB - In this paper we propose a method for constructing a spatiotemporal cortical surface atlas of neonatal brains aged between 38 and 42 weeks of gestation at the time of scan. The method is based on a spherical registration approach: multimodal surface matching (MSM) registration, where cortical folding patterns were used to drive alignment. Cortical surfaces from 44 subjects were projected onto spheres and grouped into 5 weeks, with all surfaces within each group co-registered using pairwise MSM registration in order to avoid bias in the atlas towards any of the subjects. Finally, warps were projected to the anatomical surfaces to allow averaging of white matter surfaces, and folding metrics, in the template space. Our approach improves the sharpness of the templates from what can be achieved using affine alignment alone.
KW - MRI
KW - MSM
KW - cortical surface atlas
KW - neonatal
UR - http://www.scopus.com/inward/record.url?scp=84978394250&partnerID=8YFLogxK
U2 - 10.1109/ISBI.2016.7493381
DO - 10.1109/ISBI.2016.7493381
M3 - Conference contribution
AN - SCOPUS:84978394250
T3 - Proceedings - International Symposium on Biomedical Imaging
SP - 775
EP - 778
BT - 2016 IEEE International Symposium on Biomedical Imaging
PB - IEEE Computer Society
T2 - 2016 IEEE 13th International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2016
Y2 - 13 April 2016 through 16 April 2016
ER -