TY - GEN
T1 - Construction of a dynamic 4D probabilistic atlas for the developing brain
AU - Murgasova, Maria
AU - Srinivasan, Latha
AU - Gousias, Ioannis S.
AU - Aljabar, Paul
AU - Hajnal, Joseph V.
AU - Edwards, A. David
AU - Rueckert, Daniel
PY - 2010
Y1 - 2010
N2 - Probabilistic atlases have been established in the literature as a standard tool for enhancing the intensity-based classification of brain MRI. The rapidly growing neonatal brain requires an age-specific spatial probabilistic atlas to guide the segmentation process. In this paper we describe a method for dynamically creating a probabilistic atlas for any chosen stage of neonatal brain development. The atlas is created from the segmentations of 153 subjects of different ages using a kernel regression method. For any given age, an intensity template as well as the corresponding tissue probability maps with the correct sizes and shapes of the structures can be dynamically generated. The resulting atlas provides prior tissue probability maps for six structures - cortex, white matter, subcortical gray matter, brainstem and cerebellum, for ages of 29 to 44 weeks of gestation.
AB - Probabilistic atlases have been established in the literature as a standard tool for enhancing the intensity-based classification of brain MRI. The rapidly growing neonatal brain requires an age-specific spatial probabilistic atlas to guide the segmentation process. In this paper we describe a method for dynamically creating a probabilistic atlas for any chosen stage of neonatal brain development. The atlas is created from the segmentations of 153 subjects of different ages using a kernel regression method. For any given age, an intensity template as well as the corresponding tissue probability maps with the correct sizes and shapes of the structures can be dynamically generated. The resulting atlas provides prior tissue probability maps for six structures - cortex, white matter, subcortical gray matter, brainstem and cerebellum, for ages of 29 to 44 weeks of gestation.
UR - http://www.scopus.com/inward/record.url?scp=77955226120&partnerID=8YFLogxK
U2 - 10.1109/ISBI.2010.5490145
DO - 10.1109/ISBI.2010.5490145
M3 - Conference contribution
AN - SCOPUS:77955226120
SN - 9781424441266
T3 - 2010 7th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2010 - Proceedings
SP - 952
EP - 955
BT - 2010 7th IEEE International Symposium on Biomedical Imaging
T2 - 7th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2010
Y2 - 14 April 2010 through 17 April 2010
ER -