Conformational perturbation, allosteric modulation of cellular signaling pathways, and disease in P23H rhodopsin

Keyphrases

• Cell Signaling Pathways 100%
• Allosteric Modulation 100%
• P23H rhodopsin 100%
• P23H 75%
• Dimerization 50%
• Molecular Dynamics Simulation 50%
• Structural Change 25%
• Disease Pathogenesis 25%
• Photoreceptor 25%
• Activation Mechanism 25%
• Active State 25%
• Functional Mode 25%
• Tertiary Structure 25%
• Global Modes 25%
• Torsional Dynamics 25%
• Rhodopsin 25%
• Homodimer 25%
• Conformational Stability 25%
• Most Common Cause 25%
• Dynamic Stability 25%
• Functional Dynamics 25%
• Dimerization Motif 25%
• Autosomal Dominant Retinitis pigmentosa 25%
• Cell Degeneration 25%
• THz Spectroscopy 25%
• Photoreceptor Cells 25%
• Rod Opsin 25%
• Signaling State 25%
• P23H mutation 25%

Biochemistry, Genetics and Molecular Biology

• Rhodopsin 100%
• Dynamics 40%
• Dimerization 40%
• Photoreceptor Cell 40%
• Wild Type 20%
• Tertiary Structure 20%
• Homodimerization 20%
• Autosomal Dominant Inheritance 20%
• Retinitis pigmentosa 20%
• Cell Degeneration 20%
• Opsin 20%