Concentration of polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans and dioxin-like PCBs in human adipose tissue from Turkish men

Ismet Çok, Menekse Keski Donmez, M. Hakan Satiroǧlu, Batu Aydinuraz, Bernhard Henkelmann, Jarmila Kotalik, Karl Werner Schramm

Research output: Contribution to journalArticlepeer-review

24 Scopus citations

Abstract

There is no previous report from Turkey on chemically determined polychlorinated dibenzo-para-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and dioxin-like polychlorinated biphenyls (PCBs) in human tissues expressed as World Health Organization (WHO) toxic equivalents (TEQs). The objective of this study was to determine the occurrence of PCDDs/Fs, and dioxin-like PCBs in the general adult Turkish population. For this reason we measured adipose tissue concentrations of PCDDs/Fs and dioxin-like PCBs in 23 Turkish men living in Ankara,Turkey in 2004. PCDD/F concentrations ranged between 3.2 and 19.7 pg WHO-TEQ/g fat (5.34 and 42.7 WHO-TEQ/g fat, respectively, including dioxin-like PCBs). The mean concentrations of WHOPCDD/F-TEQ and WHOPCB-TEQ were 9.2 and 6.67 pg/g on a lipid basis, respectively. Samples were analyzed for PCDD/F and twelve dioxin-like PCB congeners using high resolution gas chromatography/high resolution mass spectrometry (HRGC/HRMS). This study is very important since it is the first report on PCDDs/Fs and dioxin-like PCB contamination in human adipose tissue from Turkey.

Original languageEnglish
Pages (from-to)1955-1961
Number of pages7
JournalChemosphere
Volume66
Issue number10
DOIs
StatePublished - Jan 2007
Externally publishedYes

Keywords

  • Adipose tissue
  • Dioxin-like PCBs
  • HRGC/HRMS
  • Polychlorinated dibenzo-p-dioxins and furans
  • Turkey

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