TY - GEN
T1 - Complete valvular heart apparatus model from 4D cardiac CT
AU - Grbić, Saša
AU - Ionasec, Razvan
AU - Vitanovski, Dime
AU - Voigt, Ingmar
AU - Wang, Yang
AU - Georgescu, Bogdan
AU - Navab, Nassir
AU - Comaniciu, Dorin
PY - 2010
Y1 - 2010
N2 - The cardiac valvular apparatus, composed of the aortic, mitral, pulmonary and tricuspid valve, is an essential part of the anatomical, functional and hemodynamic mechanism of the heart and the cardiovascular system as a whole. Valvular heart diseases often involve multiple dysfunctions and require joint assessment and therapy of the valves. In this paper, we propose a complete and modular patient-specific model of the cardiac valvular apparatus estimated from 4D cardiac CT data. A new constrained Multi-linear Shape Model (cMSM), conditioned by anatomical measurements, is introduced to represent the complex spatio-temporal variation of the heart valves. The cMSM is exploited within a learning-based framework to efficiently estimate the patient-specific valve parameters from cine images. Experiments on 64 4D cardiac CT studies demonstrate the performance and clinical potential of the proposed method. To the best of our knowledge, it is the first time cardiologists and cardiac surgeons can benefit from an automatic quantitative evaluation of the complete valvular apparatus based on non-invasive imaging techniques. In conjunction with existent patient-specific chamber models, the presented valvular model enables personalized computation modeling and realistic simulation of the entire cardiac system.
AB - The cardiac valvular apparatus, composed of the aortic, mitral, pulmonary and tricuspid valve, is an essential part of the anatomical, functional and hemodynamic mechanism of the heart and the cardiovascular system as a whole. Valvular heart diseases often involve multiple dysfunctions and require joint assessment and therapy of the valves. In this paper, we propose a complete and modular patient-specific model of the cardiac valvular apparatus estimated from 4D cardiac CT data. A new constrained Multi-linear Shape Model (cMSM), conditioned by anatomical measurements, is introduced to represent the complex spatio-temporal variation of the heart valves. The cMSM is exploited within a learning-based framework to efficiently estimate the patient-specific valve parameters from cine images. Experiments on 64 4D cardiac CT studies demonstrate the performance and clinical potential of the proposed method. To the best of our knowledge, it is the first time cardiologists and cardiac surgeons can benefit from an automatic quantitative evaluation of the complete valvular apparatus based on non-invasive imaging techniques. In conjunction with existent patient-specific chamber models, the presented valvular model enables personalized computation modeling and realistic simulation of the entire cardiac system.
UR - http://www.scopus.com/inward/record.url?scp=78349234649&partnerID=8YFLogxK
U2 - 10.1007/978-3-642-15705-9_27
DO - 10.1007/978-3-642-15705-9_27
M3 - Conference contribution
C2 - 20879234
AN - SCOPUS:78349234649
SN - 3642157041
SN - 9783642157042
T3 - Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
SP - 218
EP - 226
BT - Medical Image Computing and Computer-Assisted Intervention, MICCAI2010 - 13th International Conference, Proceedings
T2 - 13th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2010
Y2 - 20 September 2010 through 24 September 2010
ER -