Comparison of dioxin-like-response in vitro and chemical analysis of emissions and materials

K. W. Schramm; C. Klimm; A. Hofmaier; A. Kettrup

doi:10.1016/S0045-6535(00)00227-7

Comparison of dioxin-like-response in vitro and chemical analysis of emissions and materials

K. W. Schramm, C. Klimm, A. Hofmaier, A. Kettrup

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

Samples from industrial and domestic emissions and materials were investigated by using in vitro assays for dioxin-like-response (DLR) and chemical analysis. The results show a small part of persistent bioaccumulative toxicants (PBT) to be responsive in vitro· Clean-up procedures directed to persistence decrease the amount of inducing toxicants substantially· The comparison of biological in vitro (B) and chemical (A) analysis show ratios between B and A below 10 for DLR of persistent inductors. The consideration of PAH improved the knowledge about unknown less persistent agonists.

Original language	English
Pages (from-to)	551-557
Number of pages	7
Journal	Chemosphere
Volume	42
Issue number	5-7
DOIs	https://doi.org/10.1016/S0045-6535(00)00227-7
State	Published - 2001
Externally published	Yes

Keywords

Ah- receptor
Ashes
Bioassay
Dioxin-like-response (DLR)
EROD
Emission
In vitro
P4501A1
PAH
PBT
PCDD/F
PHAH

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10.1016/S0045-6535(00)00227-7

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abstract = "Samples from industrial and domestic emissions and materials were investigated by using in vitro assays for dioxin-like-response (DLR) and chemical analysis. The results show a small part of persistent bioaccumulative toxicants (PBT) to be responsive in vitro· Clean-up procedures directed to persistence decrease the amount of inducing toxicants substantially· The comparison of biological in vitro (B) and chemical (A) analysis show ratios between B and A below 10 for DLR of persistent inductors. The consideration of PAH improved the knowledge about unknown less persistent agonists.",

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AU - Schramm, K. W.

AU - Klimm, C.

AU - Hofmaier, A.

AU - Kettrup, A.

PY - 2001

Y1 - 2001

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AB - Samples from industrial and domestic emissions and materials were investigated by using in vitro assays for dioxin-like-response (DLR) and chemical analysis. The results show a small part of persistent bioaccumulative toxicants (PBT) to be responsive in vitro· Clean-up procedures directed to persistence decrease the amount of inducing toxicants substantially· The comparison of biological in vitro (B) and chemical (A) analysis show ratios between B and A below 10 for DLR of persistent inductors. The consideration of PAH improved the knowledge about unknown less persistent agonists.

KW - Ah- receptor

KW - Ashes

KW - Bioassay

KW - Dioxin-like-response (DLR)

KW - EROD

KW - Emission

KW - In vitro

KW - P4501A1

KW - PAH

KW - PBT

KW - PCDD/F

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JO - Chemosphere

JF - Chemosphere

IS - 5-7

ER -

Comparison of dioxin-like-response in vitro and chemical analysis of emissions and materials

Abstract

Keywords

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