Comparison between high-field-strength MR imaging and CT for screening of hepatic metastases: A receiver operating characteristic analysis

Ernst J. Rummeny, Karl Wernecke, Sanjay Saini, Pierre Vassallo, Werner Wiesmann, Joerg W. Oestmann, Dietmar Kivelitz, Bernhard Reers, Maximilian F. Reiser, Peter E. Peters

Research output: Contribution to journalReview articlepeer-review

82 Scopus citations

Abstract

The diagnostic performance of high-field-strength magnetic resonance (MR) imaging (1.5 T) for detection of liver metastases was compared with that of computed tomography (CT). All patients (n = 52) underwent preoperative screening for metastases by means of MR imaging with T1-weighted, proton-density-weighted, and T2-weighted pulse sequences and CT scanning with unenhanced, incremental dynamic bolus-enhanced, and delayed contrast medium-enhanced techniques. Diagnostic performance was evaluated by means of receiver operating characteristic analysis in which 800 images (400 with and 400 without lesions) and five readers (4,000 observations) were used; images were obtained from patients (n = 39) in whom the same anatomic levels were available for all MR imaging and CT studies. Direct comparison between the best MR imaging technique (T2-weighted spin-echo imaging [repetition time, 2,000 msec; echo time, 70 msec]) and the best CT technique (incremental dynamic bolus CT) showed a strong trend of superiority of T2-weighted MR imaging over incremental dynamic bolus CT. No highly statistically significant difference (P ≥ .01), however, was found between these two techniques.

Original languageEnglish
Pages (from-to)879-886
Number of pages8
JournalRadiology
Volume182
Issue number3
DOIs
StatePublished - Mar 1992
Externally publishedYes

Keywords

  • Computed tomography (CT), comparative studies
  • Gastrointestinal tract, neoplasms, 70.32
  • Liver neoplasms, CT, 761.1211, 761.332
  • Liver neoplasms, MR, 761.1214, 761.332
  • Liver neoplasms, secondary, 761.332
  • Magnetic resonance (MR), comparative studies

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