CO/alkene copolymers as a promising class of biocompatible materials, 1: Examination of the in vitro toxicity

P. Reuter, R. Fuhrmann, A. Mücke, J. Voegele, B. Rieger, R. P. Franke

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

Novel 1,4-polyketones were synthesized by a PdII catalyzed copolymerization reaction from cheap technical monomers. The spectrum of mechanical properties ranges from highly crystalline, hard materials to thermoplastic, soft elastomers. The hydrophilicity of the surface is asdjustible from nonpolar to highly polar by a proper choice of the α-olefin component. This control of polymer properties is a basis for the development of new biocompatible materials. The results of standardized as well as more specific in vitro tests clearly demonstrate the nontoxicity of the investigated copolymers.

Original languageEnglish
Pages (from-to)123-130
Number of pages8
JournalMacromolecular Bioscience
Volume3
Issue number2
DOIs
StatePublished - 1 Feb 2003
Externally publishedYes

Keywords

  • Biological applications of polymers
  • Derivatives
  • Material properties
  • Poly(ether ketones)

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