Clinically Actionable Strategies for Studying Neural Influences in Cancer

Ihsan Ekin Demir, Carmen Mota Reyes, Wasfi Alrawashdeh, Güralp O. Ceyhan, Sylvie Deborde, Helmut Friess, Kivanc Görgülü, Rouzanna Istvanffy, David Jungwirth, Rohini Kuner, Maria Maryanovich, Shorook Na'ara, Simon Renders, Jami L. Saloman, Nicole N. Scheff, Hendrik Steenfadt, Pavel Stupakov, Vera Thiel, Divij Verma, Bengi Su YilmazRuth A. White, Timothy C. Wang, Richard J. Wong, Paul S. Frenette, Ziv Gil, Brian M. Davis

Research output: Contribution to journalComment/debate

18 Scopus citations


Neuro-glial activation is a recently identified hallmark of growing cancers. Targeting tumor hyperinnervation in preclinical and small clinical trials has yielded promising antitumor effects, highlighting the need of systematic analysis of neural influences in cancer (NIC). Here, we outline the strategies translating these findings from bench to the clinic.

Original languageEnglish
Pages (from-to)11-14
Number of pages4
JournalCancer Cell
Issue number1
StatePublished - 13 Jul 2020
Externally publishedYes


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