Chronic Pancreatitis

Pascal O. Berberat, Güralp O. Ceyhan, Zilvinas Dambrauskas, Markus W. Büchler, Helmut Friess

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Chronic pancreatitis is an inflammatory disease of the pancreas and is often associated with severe pain. Consequently, patients with chronic pancreatitis exhibit variable degrees of pancreatic exocrine and endocrine dysfunction. Chronic pancreatitis is a complex disease, afflicting heavy drinkers in the majority of cases, but is also associated with several other causes. Early diagnosis is still a difficult task. However, endosonography and endoscopic retrograde cholangiopancreatography (ERCP) may detect the earliest parenchymal and/or ductal changes. About 80% of patients with chronic pancreatitis can be managed by pain medication, dietary recommendations, and pancreatic enzyme supplementation. If conservative treatment fails, endoscopic and/or surgical interventions are safe and efficient therapeutic options. New organ-preserving operations lead to long-term pain relief and preservation of pancreatic function.

Original languageEnglish
Title of host publicationTextbook of Clinical Gastroenterology and Hepatology
Subtitle of host publicationSecond Edition
PublisherWiley Blackwell
Pages525-532
Number of pages8
ISBN (Print)1405191821, 9781405191821
DOIs
StatePublished - 16 Apr 2012

Keywords

  • Chronic pancreatitis
  • Differential diagnosis
  • Epidemiology
  • Function test
  • Imaging
  • Medical therapy
  • Risk factors
  • Surgical therapy
  • Symptoms

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