Chiral N-heterocyclic biscarbenes based on 1,2,4-triazole as ligands for metal-catalyzed asymmetric synthesis

Stephanie K.U. Riederer, Bettina Bechlars, Wolfgang A. Herrmann, Fritz E. Kühn

Research output: Contribution to journalArticlepeer-review

21 Scopus citations

Abstract

A facile and straightforward synthetic procedure for the preparation of new chiral bis-1,2,4-triazolium salts and their corresponding rhodium(i) biscarbene complexes are reported. It is widely applicable for the synthesis of 1,2,4-triazolium salts. The new chiral biscarbenes represent promising ligands for transition metal-catalyzed asymmetric syntheses. Their first successful application is demonstrated by the rhodium-catalyzed hydrogenation of dimethylitaconate and methyl-2-acetamidoacrylate which yielded enantioselectivities of up to 61% ee.

Original languageEnglish
Pages (from-to)41-43
Number of pages3
JournalDalton Transactions
Volume40
Issue number1
DOIs
StatePublished - 7 Jan 2011

Fingerprint

Dive into the research topics of 'Chiral N-heterocyclic biscarbenes based on 1,2,4-triazole as ligands for metal-catalyzed asymmetric synthesis'. Together they form a unique fingerprint.

Cite this