Chemicals with endocrine-disrupting potential: A threat to human health?

Helmut Greim

Research output: Contribution to journalReview articlepeer-review

14 Scopus citations


(Graph Presented) Horror scenarios have been conjured up, but how harmful, really, are the hormone-like compounds with which we come into contact daily in food, medications, and sunscreens? A xenobiotic can compete with a hormone at the hormone receptor and even block its action, as the picture shows for the estrogen receptor. To cause an observable effect, however, the potency and concentration of the xenobiotic must be sufficiently high, which fortunately is rarely the case.

Original languageEnglish
Pages (from-to)5568-5574
Number of pages7
JournalAngewandte Chemie International Edition in English
Issue number35
StatePublished - 3 Sep 2005
Externally publishedYes


  • Endocrine system
  • Environmental chemistry
  • Hormones
  • Toxicology


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