Chemical and biochemical studies for the differentiation of coagulase-positive staphylococci

K. H. Schleifer, F. Schumacher-Perdreau, F. Götz, B. Popp, V. Hájek

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The cell wall composition, the configuration of lactic acid produced from glucose under anaerobic conditions, the occurrence of fructose-1,6-diphosphate (FDP) activated l-lactate dehydrogenase (l-LDH), and the esterase pattern were determined from more than 80 strains of coagulase-positive staphylococci isolated from man and animal. Strains isolated from man, swine, bovines and hares form a rather homogencous group. They exhibit a similar cell wall composition, produce predominantly d,l-lactate and have a characteristic and simple esterase pattern. Coagulasepositive staphylococci isolated from dogs, horses, minks and pigeons are quite distinct from typical Staphylococcus aureus strains. They exhibit a different cell wall composition, produce only l-lactate, possess an l-LDH which is specifically activated by FDP, and have a quite complex esterase pattern.

Original languageEnglish
Pages (from-to)263-270
Number of pages8
JournalArchives of Microbiology
Issue number2-3
StatePublished - Nov 1976
Externally publishedYes


  • Cell wall composition
  • Coagulase-positive staphylococci
  • Esterase pattern
  • FDP-activated l-LDH
  • Lactic acid configuration
  • Staphylococcus aureus


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