Charting the Roadmap of T Cell Exhaustion

Talyn Chu; Dietmar Zehn

doi:10.1016/j.immuni.2020.04.019

Charting the Roadmap of T Cell Exhaustion

Talyn Chu, Dietmar Zehn

Chair of Animal Physiology and Immunology

Technical University of Munich

Research output: Contribution to journal › Comment/debate

18 Scopus citations

Abstract

Exposure to chronic infection or malignant tumors triggers the differentiation of functionally impaired, so-called exhausted T cells. In this issue of Immunity, Beltra et al. reveal a multi-step developmental process that defines how T cells transition from proliferating progenitors into terminally differentiated exhausted T cells.

Original language	English
Pages (from-to)	724-726
Number of pages	3
Journal	Immunity
Volume	52
Issue number	5
DOIs	https://doi.org/10.1016/j.immuni.2020.04.019
State	Published - 19 May 2020

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10.1016/j.immuni.2020.04.019

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title = "Charting the Roadmap of T Cell Exhaustion",

abstract = "Exposure to chronic infection or malignant tumors triggers the differentiation of functionally impaired, so-called exhausted T cells. In this issue of Immunity, Beltra et al. reveal a multi-step developmental process that defines how T cells transition from proliferating progenitors into terminally differentiated exhausted T cells.",

author = "Talyn Chu and Dietmar Zehn",

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AU - Zehn, Dietmar

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JF - Immunity

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Charting the Roadmap of T Cell Exhaustion

Abstract

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