Charakterisierung der spontanen Transplantattoleranz am Beispiel der orthotopen Lebertransplantation: Die Bedeutung des Fas-Ligand vermittelten programmierten Zelltodes.

F. Fändrich; X. Lin; G. Klöppel; B. Kremer

Charakterisierung der spontanen Transplantattoleranz am Beispiel der orthotopen Lebertransplantation: Die Bedeutung des Fas-Ligand vermittelten programmierten Zelltodes.

Translated title of the contribution: Characterization of spontaneous transplant tolerance exemplified by orthotopic liver transplantation: significance of Fas ligand induced programmed cell death

F. Fändrich, X. Lin, G. Klöppel, B. Kremer

Christian-Albrechts-University of Kiel

Research output: Contribution to journal › Article › peer-review

Abstract

For the first time, this study provides strong evidence that hepatocytes express functional Fas-ligand protein after orthotopic liver transplantation in specific allogeneic strain combinations. Fas-L expression correlates with intra-graft elimination of alloreactive T cells and subsequent tolerance induction. Thus, detection of Fas-L offers the possibility to be used as a marker protein for tolerized liver transplants.

Translated title of the contribution	Characterization of spontaneous transplant tolerance exemplified by orthotopic liver transplantation: significance of Fas ligand induced programmed cell death
Original language	German
Pages (from-to)	361-365
Number of pages	5
Journal	Langenbecks Archiv für Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft für Chirurgie. Kongress
Volume	115
Issue number	Suppl I
State	Published - 1998
Externally published	Yes

Cite this

Fändrich, F. ; Lin, X. ; Klöppel, G. et al. / Charakterisierung der spontanen Transplantattoleranz am Beispiel der orthotopen Lebertransplantation : Die Bedeutung des Fas-Ligand vermittelten programmierten Zelltodes. In: Langenbecks Archiv für Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft für Chirurgie. Kongress. 1998 ; Vol. 115, No. Suppl I. pp. 361-365.

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title = "Charakterisierung der spontanen Transplantattoleranz am Beispiel der orthotopen Lebertransplantation: Die Bedeutung des Fas-Ligand vermittelten programmierten Zelltodes.",

abstract = "For the first time, this study provides strong evidence that hepatocytes express functional Fas-ligand protein after orthotopic liver transplantation in specific allogeneic strain combinations. Fas-L expression correlates with intra-graft elimination of alloreactive T cells and subsequent tolerance induction. Thus, detection of Fas-L offers the possibility to be used as a marker protein for tolerized liver transplants.",

author = "F. F{\"a}ndrich and X. Lin and G. Kl{\"o}ppel and B. Kremer",

year = "1998",

language = "Deutsch",

volume = "115",

pages = "361--365",

journal = "Langenbecks Archiv f{\"u}r Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft f{\"u}r Chirurgie. Kongress",

issn = "0942-2854",

publisher = "Springer Verlag",

number = "Suppl I",

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Charakterisierung der spontanen Transplantattoleranz am Beispiel der orthotopen Lebertransplantation: Die Bedeutung des Fas-Ligand vermittelten programmierten Zelltodes. / Fändrich, F.; Lin, X.; Klöppel, G. et al.
In: Langenbecks Archiv für Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft für Chirurgie. Kongress, Vol. 115, No. Suppl I, 1998, p. 361-365.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Charakterisierung der spontanen Transplantattoleranz am Beispiel der orthotopen Lebertransplantation

T2 - Die Bedeutung des Fas-Ligand vermittelten programmierten Zelltodes.

AU - Fändrich, F.

AU - Lin, X.

AU - Klöppel, G.

AU - Kremer, B.

PY - 1998

Y1 - 1998

N2 - For the first time, this study provides strong evidence that hepatocytes express functional Fas-ligand protein after orthotopic liver transplantation in specific allogeneic strain combinations. Fas-L expression correlates with intra-graft elimination of alloreactive T cells and subsequent tolerance induction. Thus, detection of Fas-L offers the possibility to be used as a marker protein for tolerized liver transplants.

AB - For the first time, this study provides strong evidence that hepatocytes express functional Fas-ligand protein after orthotopic liver transplantation in specific allogeneic strain combinations. Fas-L expression correlates with intra-graft elimination of alloreactive T cells and subsequent tolerance induction. Thus, detection of Fas-L offers the possibility to be used as a marker protein for tolerized liver transplants.

UR - https://www.scopus.com/pages/publications/0142186350

M3 - Artikel

C2 - 14518276

AN - SCOPUS:0142186350

SN - 0942-2854

VL - 115

SP - 361

EP - 365

JO - Langenbecks Archiv für Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft für Chirurgie. Kongress

JF - Langenbecks Archiv für Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft für Chirurgie. Kongress

IS - Suppl I

ER -

Charakterisierung der spontanen Transplantattoleranz am Beispiel der orthotopen Lebertransplantation: Die Bedeutung des Fas-Ligand vermittelten programmierten Zelltodes.

Abstract

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