Characterization of the melanocortin-4-receptor nonsense mutation W16X in vitro and in vivo

Neuroscience

• In Vivo 100%
• Aminoglycoside 100%
• Melanocortin 4 Receptor 100%
• In Vitro 100%
• Nonsense Mutation 100%
• Central Nervous System 33%
• Gene Delivery 33%
• Protein Expression 33%
• Amikacin 33%
• Cell Culture 33%
• Polyphagia 33%
• Gentamicin 33%

Biochemistry, Genetics and Molecular Biology

• Nonsense Mutation 100%
• Aminoglycoside 100%
• Melanocortin 4 Receptor 100%
• Genetic Disorder 33%
• Mouse Model 33%
• Gene Targeting 33%
• Cell Culture 33%
• Allele 33%
• Protein Expression 33%
• Body Height 33%
• Amikacin 33%
• Impaired Glucose Tolerance 33%
• Gentamicin 33%

Keyphrases

• Nonsense mutation 100%
• Melanocortin 4 Receptor (MC4R) 100%
• Non-maximum Suppression 40%
• Obesity 30%
• Knock-in Mouse Model 30%
• Aminoglycosides 30%
• Stop mutation 20%
• Protein Expression 10%
• Genetic Disease 10%
• Loss Function 10%
• Central Nervous System 10%
• Mouse Model 10%
• Surface Defects 10%
• Typical Characteristics 10%
• Amikacin 10%
• Impaired Glucose Tolerance 10%
• Obese Subjects 10%
• Morbid Obesity 10%
• Surface Expression 10%
• Gene Targeting 10%
• Gentamicin 10%
• Therapeutic Trial 10%
• Hyperphagia 10%
• Cell Culture Assay 10%
• Nonsense Allele 10%