Cerebral metastasis in recurrent squamous cell carcinoma of the vulva: case report and review of the literature

Anna Jaeger, Maxine Biermann, Katharina Prieske, Donata Grimm, Astrid Grottke, Johannes Salamon, Cordula Petersen, Volkmar Mueller, Barbara Schmalfeldt, Linn Woelber

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations

Abstract

Background: Distant metastases from squamous cell cancer of the vulva (VSCC) are encountered rarely and are associated with a poor prognosis. Cerebral metastases have only been described anecdotally. Case history: A 51-year old woman was diagnosed with hepatic metastases due to VSCC. Initial therapy comprised wide local excision of the primary tumor with inguino-femoral lymphadenectomy (LAE) followed by stereotactic radiation of the singular hepatic metastasis while adjuvant chemoradiation of the vulva and lymphatics was declined. 3 years later, she subsequently developed lung and cerebral metastases. Conclusion: The course of metastatic disease in VSCC is poorly understood. Further knowledge of the metastatic patterns in vulvar cancer is required for guidance of future therapeutic interventions.

Original languageEnglish
Pages (from-to)327-332
Number of pages6
JournalArchives of Gynecology and Obstetrics
Volume301
Issue number2
DOIs
StatePublished - 1 Feb 2020
Externally publishedYes

Keywords

  • Brain metastases
  • Distant metastases
  • Prognosis
  • Squamous cell carcinoma of the vulva

Fingerprint

Dive into the research topics of 'Cerebral metastasis in recurrent squamous cell carcinoma of the vulva: case report and review of the literature'. Together they form a unique fingerprint.

Cite this