Central nervous system regulation of energy metabolism: Ghrelin versus leptin

Ruben Nogueiras, Matthias H. Tschöp, Jeffrey M. Zigman

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

101 Scopus citations


In this brief review, we introduce some major themes in the regulation of energy, lipid, and glucose metabolism by the central nervous system (CNS). Rather than comprehensively discussing the field, we instead will discuss some of the key findings made regarding the interaction of the hormones ghrelin and leptin with the CNS.

Original languageEnglish
Title of host publicationThe Maillard Reaction Recent Advances in Food and Biomedical Sciences
PublisherBlackwell Publishing Inc.
Number of pages6
ISBN (Print)9781573317, 9789781573316
StatePublished - Apr 2008
Externally publishedYes

Publication series

NameAnnals of the New York Academy of Sciences
ISSN (Print)0077-8923
ISSN (Electronic)1749-6632


  • Central nervous system
  • Energy balance equation
  • Energy partitioning
  • Ghrelin
  • Leptin
  • Melanocortin


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