Cellular assays with multiparametric bioelectronic sensor chips

Joachim Wiest; Martin Brischwein; Johann Ressler; Angela M. Otto; Helmut Grothe; Bernhard Wolf

doi:10.2533/000942905777676623

Cellular assays with multiparametric bioelectronic sensor chips

Joachim Wiest
, Martin Brischwein
, Johann Ressler
, Angela M. Otto
, Helmut Grothe
, Bernhard Wolf

Technical University of Munich

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

Abstract

During recent years, sensor chip-based systems have been developed which monitor functional changes of living cells. Key elements of such cellular assays are silicon or glass chips with integrated sensors for physicochemical parameters, i.e. pH, pO₂ electric impedance and temperature. Analysis of these primary parameters yields information about cell metabolism, cell growth and adhesion, and cell morphological changes. The operation principles of individual sensor types are described together with examples of experimental results.

Original language	English
Pages (from-to)	243-246
Number of pages	4
Journal	Chimia
Volume	59
Issue number	5
DOIs	https://doi.org/10.2533/000942905777676623
State	Published - 2005

Keywords

Cell morphology
Cell-based assay
Cellular respiration
Extracellular acidification
Sensor chip

Access to Document

10.2533/000942905777676623

Cite this

@article{06af99d41cf34419b58b4d5a08739634,

title = "Cellular assays with multiparametric bioelectronic sensor chips",

abstract = "During recent years, sensor chip-based systems have been developed which monitor functional changes of living cells. Key elements of such cellular assays are silicon or glass chips with integrated sensors for physicochemical parameters, i.e. pH, pO2 electric impedance and temperature. Analysis of these primary parameters yields information about cell metabolism, cell growth and adhesion, and cell morphological changes. The operation principles of individual sensor types are described together with examples of experimental results.",

keywords = "Cell morphology, Cell-based assay, Cellular respiration, Extracellular acidification, Sensor chip",

author = "Joachim Wiest and Martin Brischwein and Johann Ressler and Otto, \{Angela M.\} and Helmut Grothe and Bernhard Wolf",

year = "2005",

doi = "10.2533/000942905777676623",

language = "English",

volume = "59",

pages = "243--246",

journal = "Chimia",

issn = "0009-4293",

publisher = "Swiss Chemical Society",

number = "5",

}

TY - JOUR

T1 - Cellular assays with multiparametric bioelectronic sensor chips

AU - Wiest, Joachim

AU - Brischwein, Martin

AU - Ressler, Johann

AU - Otto, Angela M.

AU - Grothe, Helmut

AU - Wolf, Bernhard

PY - 2005

Y1 - 2005

N2 - During recent years, sensor chip-based systems have been developed which monitor functional changes of living cells. Key elements of such cellular assays are silicon or glass chips with integrated sensors for physicochemical parameters, i.e. pH, pO2 electric impedance and temperature. Analysis of these primary parameters yields information about cell metabolism, cell growth and adhesion, and cell morphological changes. The operation principles of individual sensor types are described together with examples of experimental results.

AB - During recent years, sensor chip-based systems have been developed which monitor functional changes of living cells. Key elements of such cellular assays are silicon or glass chips with integrated sensors for physicochemical parameters, i.e. pH, pO2 electric impedance and temperature. Analysis of these primary parameters yields information about cell metabolism, cell growth and adhesion, and cell morphological changes. The operation principles of individual sensor types are described together with examples of experimental results.

KW - Cell morphology

KW - Cell-based assay

KW - Cellular respiration

KW - Extracellular acidification

KW - Sensor chip

UR - https://www.scopus.com/pages/publications/20444378492

U2 - 10.2533/000942905777676623

DO - 10.2533/000942905777676623

M3 - Article

AN - SCOPUS:20444378492

SN - 0009-4293

VL - 59

SP - 243

EP - 246

JO - Chimia

JF - Chimia

IS - 5

ER -

Cellular assays with multiparametric bioelectronic sensor chips

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this