Cellular and Molecular Probing of Intact Human Organs

Shan Zhao; Mihail Ivilinov Todorov; Ruiyao Cai; Rami AI -Maskari; Hanno Steinke; Elisabeth Kemter; Hongcheng Mai; Zhouyi Rong; Martin Warmer; Karen Stanic; Oliver Schoppe; Johannes Christian Paetzold; Benno Gesierich; Milagros N. Wong; Tobias B. Huber; Marco Duering; Oliver Thomas Bruns; Bjoern Menze; Jan Lipfert; Victor G. Puelles; Eckhard Wolf; Ingo Bechmann; Ali Ertürk

doi:10.1016/j.cell.2020.01.030

Cellular and Molecular Probing of Intact Human Organs

Shan Zhao
, Mihail Ivilinov Todorov
, Ruiyao Cai
, Rami AI -Maskari
, Hanno Steinke
, Elisabeth Kemter
, Hongcheng Mai
, Zhouyi Rong
, Martin Warmer
, Karen Stanic
, Oliver Schoppe
, Johannes Christian Paetzold
, Benno Gesierich
, Milagros N. Wong
, Tobias B. Huber
, Marco Duering
, Oliver Thomas Bruns
, Bjoern Menze
, Jan Lipfert
, Victor G. Puelles

Eckhard Wolf, Ingo Bechmann, Ali Ertürk

Informatics 16 - Chair of Computer Aided Medical Procedures

Research output: Contribution to journal › Article › peer-review

213 Scopus citations

Abstract

Zhao et al. present an approach for intact human organ mapping that uses a new tissue permeabilization method to clear and deeply label whole organs followed by light-sheet microscopy imaging and a deep learning-based pipeline for 3D reconstruction and data analysis.

Original language	English
Pages (from-to)	796-812.e19
Journal	Cell
Volume	180
Issue number	4
DOIs	https://doi.org/10.1016/j.cell.2020.01.030
State	Published - 20 Feb 2020

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10.1016/j.cell.2020.01.030

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Zhao, S., Todorov, M. I., Cai, R., -Maskari, R. AI., Steinke, H., Kemter, E., Mai, H., Rong, Z., Warmer, M., Stanic, K., Schoppe, O., Paetzold, J. C., Gesierich, B., Wong, M. N., Huber, T. B., Duering, M., Bruns, O. T., Menze, B., Lipfert, J., ... Ertürk, A. (2020). Cellular and Molecular Probing of Intact Human Organs. Cell, 180(4), 796-812.e19. https://doi.org/10.1016/j.cell.2020.01.030

@article{69be54f16f4e496da5722bba73228080,

title = "Cellular and Molecular Probing of Intact Human Organs",

abstract = "Zhao et al. present an approach for intact human organ mapping that uses a new tissue permeabilization method to clear and deeply label whole organs followed by light-sheet microscopy imaging and a deep learning-based pipeline for 3D reconstruction and data analysis.",

author = "Shan Zhao and Todorov, \{Mihail Ivilinov\} and Ruiyao Cai and -Maskari, \{Rami AI\} and Hanno Steinke and Elisabeth Kemter and Hongcheng Mai and Zhouyi Rong and Martin Warmer and Karen Stanic and Oliver Schoppe and Paetzold, \{Johannes Christian\} and Benno Gesierich and Wong, \{Milagros N.\} and Huber, \{Tobias B.\} and Marco Duering and Bruns, \{Oliver Thomas\} and Bjoern Menze and Jan Lipfert and Puelles, \{Victor G.\} and Eckhard Wolf and Ingo Bechmann and Ali Ert{\"u}rk",

note = "Publisher Copyright: {\textcopyright} 2020 Elsevier Inc.",

year = "2020",

month = feb,

day = "20",

doi = "10.1016/j.cell.2020.01.030",

language = "English",

volume = "180",

pages = "796--812.e19",

journal = "Cell",

issn = "0092-8674",

publisher = "Elsevier B.V.",

number = "4",

}

Zhao, S, Todorov, MI, Cai, R, -Maskari, RAI, Steinke, H, Kemter, E, Mai, H, Rong, Z, Warmer, M, Stanic, K, Schoppe, O, Paetzold, JC, Gesierich, B, Wong, MN, Huber, TB, Duering, M, Bruns, OT, Menze, B, Lipfert, J, Puelles, VG, Wolf, E, Bechmann, I & Ertürk, A 2020, 'Cellular and Molecular Probing of Intact Human Organs', Cell, vol. 180, no. 4, pp. 796-812.e19. https://doi.org/10.1016/j.cell.2020.01.030

TY - JOUR

T1 - Cellular and Molecular Probing of Intact Human Organs

AU - Zhao, Shan

AU - Todorov, Mihail Ivilinov

AU - Cai, Ruiyao

AU - -Maskari, Rami AI

AU - Steinke, Hanno

AU - Kemter, Elisabeth

AU - Mai, Hongcheng

AU - Rong, Zhouyi

AU - Warmer, Martin

AU - Stanic, Karen

AU - Schoppe, Oliver

AU - Paetzold, Johannes Christian

AU - Gesierich, Benno

AU - Wong, Milagros N.

AU - Huber, Tobias B.

AU - Duering, Marco

AU - Bruns, Oliver Thomas

AU - Menze, Bjoern

AU - Lipfert, Jan

AU - Puelles, Victor G.

AU - Wolf, Eckhard

AU - Bechmann, Ingo

AU - Ertürk, Ali

PY - 2020/2/20

Y1 - 2020/2/20

N2 - Zhao et al. present an approach for intact human organ mapping that uses a new tissue permeabilization method to clear and deeply label whole organs followed by light-sheet microscopy imaging and a deep learning-based pipeline for 3D reconstruction and data analysis.

AB - Zhao et al. present an approach for intact human organ mapping that uses a new tissue permeabilization method to clear and deeply label whole organs followed by light-sheet microscopy imaging and a deep learning-based pipeline for 3D reconstruction and data analysis.

UR - https://www.scopus.com/pages/publications/85079328469

U2 - 10.1016/j.cell.2020.01.030

DO - 10.1016/j.cell.2020.01.030

M3 - Article

C2 - 32059778

AN - SCOPUS:85079328469

SN - 0092-8674

VL - 180

SP - 796-812.e19

JO - Cell

JF - Cell

IS - 4

ER -

Cellular and Molecular Probing of Intact Human Organs

Abstract

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