Cellular and Molecular Probing of Intact Human Organs

Shan Zhao; Mihail Ivilinov Todorov; Ruiyao Cai; Rami AI -Maskari; Hanno Steinke; Elisabeth Kemter; Hongcheng Mai; Zhouyi Rong; Martin Warmer; Karen Stanic; Oliver Schoppe; Johannes Christian Paetzold; Benno Gesierich; Milagros N. Wong; Tobias B. Huber; Marco Duering; Oliver Thomas Bruns; Bjoern Menze; Jan Lipfert; Victor G. Puelles; Eckhard Wolf; Ingo Bechmann; Ali Ertürk

doi:10.1016/j.cell.2020.01.030

Cellular and Molecular Probing of Intact Human Organs

Shan Zhao, Mihail Ivilinov Todorov, Ruiyao Cai, Rami AI -Maskari, Hanno Steinke, Elisabeth Kemter, Hongcheng Mai, Zhouyi Rong, Martin Warmer, Karen Stanic, Oliver Schoppe, Johannes Christian Paetzold, Benno Gesierich, Milagros N. Wong, Tobias B. Huber, Marco Duering, Oliver Thomas Bruns, Bjoern Menze, Jan Lipfert, Victor G. PuellesEckhard Wolf, Ingo Bechmann, Ali Ertürk

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Abstract

Zhao et al. present an approach for intact human organ mapping that uses a new tissue permeabilization method to clear and deeply label whole organs followed by light-sheet microscopy imaging and a deep learning-based pipeline for 3D reconstruction and data analysis.

Original language	English
Pages (from-to)	796-812.e19
Journal	Cell
Volume	180
Issue number	4
DOIs	https://doi.org/10.1016/j.cell.2020.01.030
State	Published - 20 Feb 2020

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Zhao, S., Todorov, M. I., Cai, R., -Maskari, R. AI., Steinke, H., Kemter, E., Mai, H., Rong, Z., Warmer, M., Stanic, K., Schoppe, O., Paetzold, J. C., Gesierich, B., Wong, M. N., Huber, T. B., Duering, M., Bruns, O. T., Menze, B., Lipfert, J., ... Ertürk, A. (2020). Cellular and Molecular Probing of Intact Human Organs. Cell, 180(4), 796-812.e19. https://doi.org/10.1016/j.cell.2020.01.030

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title = "Cellular and Molecular Probing of Intact Human Organs",

abstract = "Zhao et al. present an approach for intact human organ mapping that uses a new tissue permeabilization method to clear and deeply label whole organs followed by light-sheet microscopy imaging and a deep learning-based pipeline for 3D reconstruction and data analysis.",

author = "Shan Zhao and Todorov, {Mihail Ivilinov} and Ruiyao Cai and -Maskari, {Rami AI} and Hanno Steinke and Elisabeth Kemter and Hongcheng Mai and Zhouyi Rong and Martin Warmer and Karen Stanic and Oliver Schoppe and Paetzold, {Johannes Christian} and Benno Gesierich and Wong, {Milagros N.} and Huber, {Tobias B.} and Marco Duering and Bruns, {Oliver Thomas} and Bjoern Menze and Jan Lipfert and Puelles, {Victor G.} and Eckhard Wolf and Ingo Bechmann and Ali Ert{\"u}rk",

note = "Publisher Copyright: {\textcopyright} 2020 Elsevier Inc.",

year = "2020",

month = feb,

day = "20",

doi = "10.1016/j.cell.2020.01.030",

language = "English",

volume = "180",

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journal = "Cell",

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Zhao, S, Todorov, MI, Cai, R, -Maskari, RAI, Steinke, H, Kemter, E, Mai, H, Rong, Z, Warmer, M, Stanic, K, Schoppe, O, Paetzold, JC, Gesierich, B, Wong, MN, Huber, TB, Duering, M, Bruns, OT, Menze, B, Lipfert, J, Puelles, VG, Wolf, E, Bechmann, I & Ertürk, A 2020, 'Cellular and Molecular Probing of Intact Human Organs', Cell, vol. 180, no. 4, pp. 796-812.e19. https://doi.org/10.1016/j.cell.2020.01.030

TY - JOUR

T1 - Cellular and Molecular Probing of Intact Human Organs

AU - Zhao, Shan

AU - Todorov, Mihail Ivilinov

AU - Cai, Ruiyao

AU - -Maskari, Rami AI

AU - Steinke, Hanno

AU - Kemter, Elisabeth

AU - Mai, Hongcheng

AU - Rong, Zhouyi

AU - Warmer, Martin

AU - Stanic, Karen

AU - Schoppe, Oliver

AU - Paetzold, Johannes Christian

AU - Gesierich, Benno

AU - Wong, Milagros N.

AU - Huber, Tobias B.

AU - Duering, Marco

AU - Bruns, Oliver Thomas

AU - Menze, Bjoern

AU - Lipfert, Jan

AU - Puelles, Victor G.

AU - Wolf, Eckhard

AU - Bechmann, Ingo

AU - Ertürk, Ali

PY - 2020/2/20

Y1 - 2020/2/20

N2 - Zhao et al. present an approach for intact human organ mapping that uses a new tissue permeabilization method to clear and deeply label whole organs followed by light-sheet microscopy imaging and a deep learning-based pipeline for 3D reconstruction and data analysis.

AB - Zhao et al. present an approach for intact human organ mapping that uses a new tissue permeabilization method to clear and deeply label whole organs followed by light-sheet microscopy imaging and a deep learning-based pipeline for 3D reconstruction and data analysis.

UR - http://www.scopus.com/inward/record.url?scp=85079328469&partnerID=8YFLogxK

U2 - 10.1016/j.cell.2020.01.030

DO - 10.1016/j.cell.2020.01.030

M3 - Article

C2 - 32059778

AN - SCOPUS:85079328469

SN - 0092-8674

VL - 180

SP - 796-812.e19

JO - Cell

JF - Cell

IS - 4

ER -

Cellular and Molecular Probing of Intact Human Organs

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