Cell division tracking and expansion of hematopoietic long-term repopulating cells

R. A.J. Oostendorp, J. Audet, C. Miller, C. J. Eaves

Research output: Contribution to journalEditorial

18 Scopus citations

Abstract

The combined use of rigorous assays for quantitating transplantable stem cell numbers and precise cell labeling and tracking procedures have provided definitive evidence that stem cell self-renewal divisions can occur in vitro in the absence of stromal feeder layers. These findings set the stage for defining conditions that may alter the ability of these cells to maintain their primitive status when mitogenically activated.

Original languageEnglish
Pages (from-to)499-501
Number of pages3
JournalLeukemia
Volume13
Issue number4
DOIs
StatePublished - 1999
Externally publishedYes

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