Catching filopodia: Exosomes surf on fast highways to enter cells

Anja Schneider, Mikael Simons

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

The mechanisms of exosomal uptake and their intracellular itinerary are not understood. In this issue, Heusermann et al. (2016. J Cell. Biol. http://dx.doi.org/10.1083/jcb.201506084) show that exosomes surf filopodia and are endocytosed in a process reminiscent to virus entry. Intraendosomal exosomes travel to the ER and are distributed to lysosomal compartments.

Original languageEnglish
Pages (from-to)143-145
Number of pages3
JournalJournal of Cell Biology
Volume213
Issue number2
DOIs
StatePublished - 1 Apr 2016
Externally publishedYes

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