Catching filopodia: Exosomes surf on fast highways to enter cells

Anja Schneider; Mikael Simons

doi:10.1083/jcb.201604024

Catching filopodia: Exosomes surf on fast highways to enter cells

Anja Schneider, Mikael Simons

Medicine and Health

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Abstract

The mechanisms of exosomal uptake and their intracellular itinerary are not understood. In this issue, Heusermann et al. (2016. J Cell. Biol. http://dx.doi.org/10.1083/jcb.201506084) show that exosomes surf filopodia and are endocytosed in a process reminiscent to virus entry. Intraendosomal exosomes travel to the ER and are distributed to lysosomal compartments.

Original language	English
Pages (from-to)	143-145
Number of pages	3
Journal	Journal of Cell Biology
Volume	213
Issue number	2
DOIs	https://doi.org/10.1083/jcb.201604024
State	Published - 1 Apr 2016

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abstract = "The mechanisms of exosomal uptake and their intracellular itinerary are not understood. In this issue, Heusermann et al. (2016. J Cell. Biol. http://dx.doi.org/10.1083/jcb.201506084) show that exosomes surf filopodia and are endocytosed in a process reminiscent to virus entry. Intraendosomal exosomes travel to the ER and are distributed to lysosomal compartments.",

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Catching filopodia: Exosomes surf on fast highways to enter cells

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