Cardio-specific long-term gene expression in a porcine model after selective pressure-regulated retroinfusion of adeno-associated viral (AAV) vectors

Keyphrases

• Adeno-associated Viral 100%
• Adeno-associated Viral Vector 100%
• Cardiac Gene Therapy 14%
• Cardiac Veins 28%
• Cardio 100%
• Cardiomyocytes 14%
• Co-application 14%
• Coronary Veins 14%
• Cytomegalovirus 28%
• Expression Level 14%
• Gene of Interest 14%
• Gene Transfer 28%
• Heparin Binding Site 14%
• Interventricular 14%
• Large Animal Model 14%
• Left Anterior Descending 28%
• Liver 14%
• Long-term Expression 14%
• Long-term Gene Expression 100%
• Luciferase Activity 14%
• Luciferase Reporter Gene 14%
• Lung 14%
• Myocardium 14%
• Myosin Light Chain 14%
• P Factor 14%
• Peripheral Tissues 14%
• Porcine Heart 14%
• Porcine Model 100%
• Preclinical Evaluation 14%
• Recombinant Human Vascular Endothelial Growth Factor 14%
• Reporter Gene Expression 28%
• Retroinfusion 100%
• Rodent Animal Model 14%
• Selective Pressure 100%
• Serotype 6 14%
• Species-dependent 14%
• Transduction Efficiency 14%
• Transfer Efficiency 14%
• Transgene Expression 28%
• Vascular Endothelial Growth Factor 42%
• Vector Genomes 28%
• Vector System 14%
• Viral Genome 14%

Biochemistry, Genetics and Molecular Biology

• Adeno Associated Virus Vector 100%
• Animal Model 50%
• Binding Site 25%
• Cardiac Muscle Cell 25%
• Cytomegalovirus 50%
• Gene Expression 100%
• Gene Therapy 25%
• Heparin 25%
• Luciferase 50%
• Myosin Light Chain 25%
• Pig 25%
• Porcine Model 100%
• Promoter Region 25%
• Reporter Gene 75%
• Serotype 25%
• Transgene 50%
• Vascular Endothelial Growth Factor 100%
• Virus Genome 25%