Cardiac MRI derived epicardial fat maps to assist VT ablation procedures for subjects with implantable devices

Judith Zimmermann, Shams Rashid, Peng Hu, Amin Katouzian, Nassir Navab, Daniel B. Ennis

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Scopus citations

Abstract

Cardiac electroanatomical mapping (EAM) to locate myocardial scar substrate during ventricular tachycardia (VT) ablation therapy is currently faced with a major limitation. The presence of epicardial fat leads to false-positive low-voltage maps that may interpreted as myocardial scar. Pre-procedural cardiac magnetic resonance (CMR) imaging can produce images of the heart in which both cardiac geometry and epicardial fat are particularly conspicuous. The goal of the present work is to build CMR based geometric models composed of a shell of the cardiac anatomy and epicardial fat. Herein, we first defined a black-blood imaging protocol that is feasible in patients with implanted devices. Then a semi-automated image segmentation method was developed and applied to extract ventricular surface anatomy and epicardial fat maps from which three-dimensional surfaces were built. The results suggest that deriving maps of epicardial fat from MRI data is feasible, accurate when compared to expert observers, and suitable for integration in a clinical catheter-based ablation procedure.

Original languageEnglish
Title of host publication2015 IEEE 12th International Symposium on Biomedical Imaging, ISBI 2015
PublisherIEEE Computer Society
Pages747-750
Number of pages4
ISBN (Electronic)9781479923748
DOIs
StatePublished - 21 Jul 2015
Event12th IEEE International Symposium on Biomedical Imaging, ISBI 2015 - Brooklyn, United States
Duration: 16 Apr 201519 Apr 2015

Publication series

NameProceedings - International Symposium on Biomedical Imaging
Volume2015-July
ISSN (Print)1945-7928
ISSN (Electronic)1945-8452

Conference

Conference12th IEEE International Symposium on Biomedical Imaging, ISBI 2015
Country/TerritoryUnited States
CityBrooklyn
Period16/04/1519/04/15

Keywords

  • Cardiac MRI
  • Epicardial Fat
  • Image Based Modeling
  • Image Segmentation
  • Implantable Cardioverter Defibrillators

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