Carbonic anhydrase inhibitors: The first selective, membrane-impermeant inhibitors targeting the tumor-associated isozyme IX

Keyphrases

• Active Sites 20%
• Antitumor Agents 20%
• Carbonic Anhydrase Inhibitors 100%
• Carbonic Anhydrase IX 100%
• Carbonic Anhydrase IX Inhibitors 20%
• Clinically Significant 20%
• Disease Prognosis 20%
• Disease Progression 20%
• High Affinity 20%
• Highly Active 20%
• Impermeability 20%
• Inhibition Profiles 20%
• Isozymes 100%
• Membrane Binding 20%
• Physiologically Relevant 20%
• Positively Charged 20%
• Pyridinium Derivatives 20%
• Selective Membrane 100%
• Specific Inhibitor 20%
• Sulfanilamide 20%
• Sulfonamides 20%
• Transmembrane 20%
• Tumor Tissue 20%
• Tumor-associated 100%
• Worse Prognosis 20%

Pharmacology, Toxicology and Pharmaceutical Science

• Carbonate Dehydratase Inhibitor 100%
• Carbonate Dehydratase IX 100%
• Disease Exacerbation 16%
• Isoenzyme 100%
• Mafenide 16%
• Neoplasm 100%
• Pyridinium Derivative 16%
• Sulfanilamide 16%
• Sulfonamide 16%

Biochemistry, Genetics and Molecular Biology

• Active Site 16%
• Carbonic Anhydrase 100%
• Carbonic Anhydrase Inhibitor 100%
• Isoenzyme 100%
• Sulfanilamide 16%
• Sulfonamide 16%