TY - JOUR
T1 - CA 494—a new tumor marker for the diagnosis of pancreatic cancer
AU - Friess, Helmut
AU - Büchler, Markus
AU - Auerbach, Bernhard
AU - Weber, Alexander
AU - Malfertheiner, Peter
AU - Hammer, Kai
AU - Madry, Norbert
AU - Greiner, Sabine
AU - Bosslet, Klaus
AU - Beger, Hans G.
PY - 1993/3/12
Y1 - 1993/3/12
N2 - In 59 patients with ductal pancreatic cancer the monoclonal antibody (MAb) BW 494, which detects the CA 494 glycoprotein antigen, was analyzed in comparison with the reference tumor markers CA 19‐9 and CEA. Eighty‐one patients with non‐pancreatic malignancies of the gastraintestinal (GI) tract, 95 with chronic pancreatitis, 124 with benign non‐pancreatic GI diseases, 30 with diabetes mellitus (type I or type II) and I14 healthy blood donors served as controls. The sensitivity of pancreatic cancer was 90%, 44% and 90% for CA 19‐9, CEA and CA 494, respectively. In chronic pancreatitis, as the most important control population for pancreatic cancer, the specificity was 85%, 72% and 94% for CA 19‐9, CEA and CA 494, respectively.
AB - In 59 patients with ductal pancreatic cancer the monoclonal antibody (MAb) BW 494, which detects the CA 494 glycoprotein antigen, was analyzed in comparison with the reference tumor markers CA 19‐9 and CEA. Eighty‐one patients with non‐pancreatic malignancies of the gastraintestinal (GI) tract, 95 with chronic pancreatitis, 124 with benign non‐pancreatic GI diseases, 30 with diabetes mellitus (type I or type II) and I14 healthy blood donors served as controls. The sensitivity of pancreatic cancer was 90%, 44% and 90% for CA 19‐9, CEA and CA 494, respectively. In chronic pancreatitis, as the most important control population for pancreatic cancer, the specificity was 85%, 72% and 94% for CA 19‐9, CEA and CA 494, respectively.
UR - http://www.scopus.com/inward/record.url?scp=0027460427&partnerID=8YFLogxK
U2 - 10.1002/ijc.2910530509
DO - 10.1002/ijc.2910530509
M3 - Article
C2 - 8449599
AN - SCOPUS:0027460427
SN - 0020-7136
VL - 53
SP - 759
EP - 763
JO - International Journal of Cancer
JF - International Journal of Cancer
IS - 5
ER -
