Bioreactor and scaffold design for the mechanical stimulation of silk based anterior cruciate ligament grafts

M. Hohlrieder; K. Cicha; A. Teuschl; M. Van Griensven; H. Redl; J. Stampfl

doi:10.1007/978-3-642-03900-3_60

Bioreactor and scaffold design for the mechanical stimulation of silk based anterior cruciate ligament grafts

M. Hohlrieder, K. Cicha, A. Teuschl, M. Van Griensven, H. Redl, J. Stampfl

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

1 Scopus citations

Abstract

A bioreactor for the mechanical stimulation of silk based scaffolds has been developed. The bioreactor simulates the natural movement of the anterior cruciate ligament by applying a biaxial movement on the scaffold. The silk scaffolds are prepared in a way that mimicks the mechanical properties (strength, stiffness) of natural anterior cruciate ligaments. The influence of degumming on the mechanical properties of the scaffolds is investigated and first results on cell cultivation experiments with fibroblasts are presented.

Original language	English
Title of host publication	World Congress on Medical Physics and Biomedical Engineering
Subtitle of host publication	Biomaterials, Cellular and Tissue Engineering, Artificial Organs
Publisher	Springer Verlag
Pages	208-210
Number of pages	3
Edition	10
ISBN (Print)	9783642038990
DOIs	https://doi.org/10.1007/978-3-642-03900-3_60
State	Published - 2009
Externally published	Yes
Event	World Congress on Medical Physics and Biomedical Engineering: Biomaterials, Cellular and Tissue Engineering, Artificial Organs - Munich, Germany Duration: 7 Sep 2009 → 12 Sep 2009

Publication series

Name	IFMBE Proceedings
Number	10
Volume	25
ISSN (Print)	1680-0737

Conference

Conference	World Congress on Medical Physics and Biomedical Engineering: Biomaterials, Cellular and Tissue Engineering, Artificial Organs
Country/Territory	Germany
City	Munich
Period	7/09/09 → 12/09/09

Keywords

Anterior cruciate ligament
Bioreactor
Mechanical properties
Silk scaffold

Access to Document

10.1007/978-3-642-03900-3_60

Cite this

Hohlrieder, M., Cicha, K., Teuschl, A., Van Griensven, M., Redl, H., & Stampfl, J. (2009). Bioreactor and scaffold design for the mechanical stimulation of silk based anterior cruciate ligament grafts. In World Congress on Medical Physics and Biomedical Engineering: Biomaterials, Cellular and Tissue Engineering, Artificial Organs (10 ed., pp. 208-210). (IFMBE Proceedings; Vol. 25, No. 10). Springer Verlag. https://doi.org/10.1007/978-3-642-03900-3_60

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abstract = "A bioreactor for the mechanical stimulation of silk based scaffolds has been developed. The bioreactor simulates the natural movement of the anterior cruciate ligament by applying a biaxial movement on the scaffold. The silk scaffolds are prepared in a way that mimicks the mechanical properties (strength, stiffness) of natural anterior cruciate ligaments. The influence of degumming on the mechanical properties of the scaffolds is investigated and first results on cell cultivation experiments with fibroblasts are presented.",

keywords = "Anterior cruciate ligament, Bioreactor, Mechanical properties, Silk scaffold",

author = "M. Hohlrieder and K. Cicha and A. Teuschl and {Van Griensven}, M. and H. Redl and J. Stampfl",

year = "2009",

doi = "10.1007/978-3-642-03900-3_60",

language = "English",

isbn = "9783642038990",

series = "IFMBE Proceedings",

publisher = "Springer Verlag",

number = "10",

pages = "208--210",

booktitle = "World Congress on Medical Physics and Biomedical Engineering",

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Hohlrieder, M, Cicha, K, Teuschl, A, Van Griensven, M, Redl, H & Stampfl, J 2009, Bioreactor and scaffold design for the mechanical stimulation of silk based anterior cruciate ligament grafts. in World Congress on Medical Physics and Biomedical Engineering: Biomaterials, Cellular and Tissue Engineering, Artificial Organs. 10 edn, IFMBE Proceedings, no. 10, vol. 25, Springer Verlag, pp. 208-210, World Congress on Medical Physics and Biomedical Engineering: Biomaterials, Cellular and Tissue Engineering, Artificial Organs, Munich, Germany, 7/09/09. https://doi.org/10.1007/978-3-642-03900-3_60

Bioreactor and scaffold design for the mechanical stimulation of silk based anterior cruciate ligament grafts. / Hohlrieder, M.; Cicha, K.; Teuschl, A. et al.
World Congress on Medical Physics and Biomedical Engineering: Biomaterials, Cellular and Tissue Engineering, Artificial Organs. 10. ed. Springer Verlag, 2009. p. 208-210 (IFMBE Proceedings; Vol. 25, No. 10).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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Hohlrieder M, Cicha K, Teuschl A, Van Griensven M, Redl H, Stampfl J. Bioreactor and scaffold design for the mechanical stimulation of silk based anterior cruciate ligament grafts. In World Congress on Medical Physics and Biomedical Engineering: Biomaterials, Cellular and Tissue Engineering, Artificial Organs. 10 ed. Springer Verlag. 2009. p. 208-210. (IFMBE Proceedings; 10). doi: 10.1007/978-3-642-03900-3_60

Bioreactor and scaffold design for the mechanical stimulation of silk based anterior cruciate ligament grafts

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