Biophysical characteristics of healthy skin and nonlesional skin in atopic dermatitis: Short-term effects of ultraviolet A and B irradiation

Juliane Habig, Elisabeth Vocks, Florian Kautzky, Johannes Ring

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

The present study was designed to evaluate basic differences in surface structure and viscoelastic properties of nonatopic versus atopic skin and facultative acute changes following ultraviolet irradiation. Therefore, biophysical measurements by means of profilometry and cutometry were carried out on sun-protected unaffected gluteal skin areas in both groups before and 24 h after single UVA and UVB irradiations. The results indicate that the clinically unaffected skin of patients with atopic eczema differs from normal skin in terms of increased roughness parameters, but not concerning depth of furrows or viscoelastic properties (viscosity and biological elasticity, cutometrically calculated). Single UVA irradiation with 50 J/cm2 induced neither measurable changes in the skin's surface structure nor in its viscoelastic properties in both groups after 24 h. However, irradiation with a single erythemogenic dose of 1 MED UVB was followed by a short-term significant increase in the depths of furrows and decrease in biological elasticity in normal and atopic skin, accompanied by an increase in viscosity in normal skin. Copyright (C) 2000 S. Karger AG, Basel.

Original languageEnglish
Pages (from-to)174-181
Number of pages8
JournalSkin Pharmacology and Applied Skin Physiology
Volume13
Issue number3-4
DOIs
StatePublished - 2000

Keywords

  • Atopic eczema
  • Cutometry
  • Photodamage
  • Profilometry
  • Skin surface
  • Viscoelasticity

Fingerprint

Dive into the research topics of 'Biophysical characteristics of healthy skin and nonlesional skin in atopic dermatitis: Short-term effects of ultraviolet A and B irradiation'. Together they form a unique fingerprint.

Cite this