Biomolekulare nanotechnologie: Faltkunst mit DNA-origami

Many processes in biology rely fundamentally on the relative position and orientation of interacting molecules. It is notoriously difficult to observe, let alone control, the position and orientation of molecules because of their small size and the constant thermal fluctuations that they experience. Molecular self-assembly with DNA origami enables building customshaped nanometer-scale objects with molecular weights in the mega - dalton regime. It provides a unique route for placing molecules and constraining their fluctuations in user-defined ways and thus opens up completely new avenues for scientific exploration.