Abstract
For generation of animal models with defined mutations by homologous recombination we established a strategy based on transfection of porcine primary cells with modified BACs to subsequently generate animals by nuclear transfer.
Translated title of the contribution | Biomedical research: Targeted mutations for the generation of large animal models |
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Original language | German |
Pages (from-to) | 541-544 |
Number of pages | 4 |
Journal | BioSpektrum |
Volume | 17 |
Issue number | 5 |
DOIs | |
State | Published - Sep 2011 |
Externally published | Yes |