Biomedizinische forschung: Zielgerichtete mutationen zur erzeugung von großtiermodellen

Translated title of the contribution: Biomedical research: Targeted mutations for the generation of large animal models

Nikolai Klymiuk, Annegret Wünsch, Eckhard Wolf

Research output: Contribution to journalArticlepeer-review

Abstract

For generation of animal models with defined mutations by homologous recombination we established a strategy based on transfection of porcine primary cells with modified BACs to subsequently generate animals by nuclear transfer.

Translated title of the contributionBiomedical research: Targeted mutations for the generation of large animal models
Original languageGerman
Pages (from-to)541-544
Number of pages4
JournalBioSpektrum
Volume17
Issue number5
DOIs
StatePublished - Sep 2011
Externally publishedYes

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