Bioconcentration potential (BCP) of 2,3,7,8-Tetrachlorodibenzop-dioxin (2,3,7,8-TCDD) in terrestrial organisms including humans

Harald J. Geyer, Irene Scheunert, Johannes G. Filser, Friedhelm Korte

Research output: Contribution to journalArticlepeer-review

28 Scopus citations

Abstract

The bioconcentration factors (BCFs) of 2,3,7,8-TCDD in adipose tissue of rats, beef cattle and monkeys have been calculated. The bioconcentration potential of TCDD in man was calculated by two indirect methods: 1) from daily intake of TCDD and its measured concentrations in adipose tissues and 2) from measured half-life and measured concentrations in body fat at steady state using a linear one compartment pharmacokinetic model. The BCFs in humans calculated by both methods are between 104 and 206, or 153, respectively.

Original languageEnglish
Pages (from-to)1495-1502
Number of pages8
JournalChemosphere
Volume15
Issue number9-12
DOIs
StatePublished - 1986
Externally publishedYes

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