Biochemical model reactions on the prooxidative activity of homocysteine

Gudrun Preibisch, Christina Küffner, Erich F. Elstner

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

The sulfur amino acid homocysteine has recently been addressed as marker for vessel damaging and atherosclerotic dispositions. The atherogenic index has been correlated with the one of cholesterol and is significantly higher in cholesterinemic as compared to normal lipidemic persons. In the present comm unication biochemical model reactions are presented indicating the prooxidative activity o f hom ocysteine where a cooperative effect with the transition-metals copper and iron is indicated.

Original languageEnglish
Pages (from-to)58-62
Number of pages5
JournalZeitschrift fur Naturforschung - Section C Journal of Biosciences
Volume48
Issue number1-2
DOIs
StatePublished - 1993

Keywords

  • Atherogenesis
  • Homocysteine
  • Oxygen Activation

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