Abstract
The following topics are explored in this collection of commentaries on treatments of adenocarcinomas related to Barrett's esophagus: the importance of intraoperative frozen sections of the margins for the detection of high dysplasia; the preferable way for sentinel node dissection; the current role of robotic surgery and of video-endoscopic approach; the value of the Siewert's classification of adenocarcinomas; the indications of two-step esophagectomy; the evaluation of pathological complete response; the role of PET scan in staging and response assessment; the role of p53 in the selection of adenocarcinomas patients; chemotherapy regimens for adenocarcinomas; the use of monoclonal antibodies in the control of cell proliferation; he attempt to define a stage-specific strategy, and the possible indications of selective therapy; and changes in mortality rates from esophageal cancer.
Original language | English |
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Pages (from-to) | 265-291 |
Number of pages | 27 |
Journal | Annals of the New York Academy of Sciences |
Volume | 1232 |
Issue number | 1 |
DOIs | |
State | Published - Sep 2011 |
Keywords
- 5-FU
- AEG
- Adenocarcinoma
- Adenovirus vector
- Barrett's esophagus
- Chemoradiation
- Chemoradiotherapy
- Cisplatin
- EGFR
- Esophageal cancer
- FDG PET scan
- FOLFOX
- Gamma probe
- Gefitinib
- HER2
- High risk patients
- Integrated PET/CT scan
- Lymphadenectomy
- Minimally invasive esophagectomy
- Molecular markers
- Multimodality therapy
- Neoadjuvant chemotherapy
- P53
- PET tracer
- Prognosis
- R0 resection
- Radiotherapy
- Residual disease
- Robot assisted thoracolaparoscopic esophagectomy
- Robotic surgery
- Sentinel lymph nodes
- Sentinel node
- Siewert 's classification
- Submucosal invasion
- Two-stade esophagectomy