Bacterial computing with engineered populations

Martyn Amos, Ilka Maria Axmann, Nils Blüthgen, Fernando De La Cruz, Alfonso Jaramillo, Alfonso Rodriguez-Paton, Friedrich Simmel

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


We describe strategies for the construction of bacterial computing platforms by describing a number of results from the recently completed bacterial computing with engineered populations project. In general, the implementation of such systems requires a framework containing various components such as intracellular circuits, single cell input/output and cell-cell interfacing, as well as extensive analysis. In this overview paper, we describe our approach to each of these, and suggest possible areas for future research.

Original languageEnglish
Article number20140218
JournalPhilosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences
Issue number2046
StatePublished - 28 Jul 2015


  • Conjugation
  • Mathematical modelling
  • Simulation
  • Synthetic biology
  • Unconventional computing


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