Automatic segmentation and tracking of thrombus formation within in vitro microscopic video sequences

Loic Peter, Nicolas Brieu, Sjoert Jansen, Peter A. Smethurst, Willem H. Ouwehand, Nassir Navab

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Scopus citations

Abstract

There is a need to more accurately link human genetic variance with thrombotic risk. Thrombus formation results from adhesion of blood platelets to a site of injury, followed by their progressive aggregation and occasional embolization. To observe this in vitro, blood is perfused over a surface of collagen fibres, during video microscopy. This paper proposes three complementary gradient-based features which, if included in a regularized machine learning framework, yield the accurate segmentation of thrombi during such acquisitions. A novel tracking method of thrombi as deformable growing objects under split and merge conditions is also introduced.

Original languageEnglish
Title of host publication2012 9th IEEE International Symposium on Biomedical Imaging
Subtitle of host publicationFrom Nano to Macro, ISBI 2012 - Proceedings
Pages1635-1638
Number of pages4
DOIs
StatePublished - 2012
Event2012 9th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2012 - Barcelona, Spain
Duration: 2 May 20125 May 2012

Publication series

NameProceedings - International Symposium on Biomedical Imaging
ISSN (Print)1945-7928
ISSN (Electronic)1945-8452

Conference

Conference2012 9th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2012
Country/TerritorySpain
CityBarcelona
Period2/05/125/05/12

Keywords

  • Microscopy image analysis
  • segmentation
  • supervised classification
  • thrombus formation
  • tracking

Fingerprint

Dive into the research topics of 'Automatic segmentation and tracking of thrombus formation within in vitro microscopic video sequences'. Together they form a unique fingerprint.

Cite this