@inproceedings{8b457f2324304e99b2c44939328d500d,
title = "Automated quantification and analysis of mandibular asymmetry",
abstract = "We present an automated method of spatially detailed 3D asymmetry quantification in mandibles extracted from CT and apply it to a population of infants with unilateral coronal synostosis (UCS). An atlas-based method employing non-rigid registration of surfaces is used for determining deformation fields, thereby establishing detailed anatomical point correspondence between subjects as well as between points on the left and right side of the mid-sagittal plane (MSP). Asymmetry is defined in terms of the vector between a point and the corresponding anatomical point on the opposite side of the MSP after mirroring the mandible across the MSP. A principal components analysis of asymmetry characterizes the major types of asymmetry in the population, and successfully separates the asymmetric UCS mandibles from a number of less asymmetric mandibles from a control population.",
keywords = "Asymmetry, Atlas-based methods, Craniofacial malformations, Non-rigid registration, Unilateral coronal synostosis",
author = "Darvann, {Tron A.} and Hermann, {Nuno V.} and Per Larsen and Hildur {\'O}lafsdottir and Hansen, {Izabella V.} and Hove, {Hanne D.} and Leif Christensen and Daniel Rueckert and Sven Kreiborg",
year = "2010",
doi = "10.1109/ISBI.2010.5490320",
language = "English",
isbn = "9781424441266",
series = "2010 7th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2010 - Proceedings",
pages = "416--419",
booktitle = "2010 7th IEEE International Symposium on Biomedical Imaging",
note = "7th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2010 ; Conference date: 14-04-2010 Through 17-04-2010",
}