Autofluorescence removal from fluorescence molecular tomography data

Giannis Zacharakis, Anikitos Garofalakis, Stelios Psycharakis, Heiko Meyer, Clio Mamalaki, Georgia Fousteri, Joseph Papamatheakis, Dimitris Kioussis, Vasilis Ntziachristos, Eleftherios N. Economou, Jorge Ripoll

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

We present a study on three-dimensional mapping and removal of autofluorescence from fluorescence molecular tomography (FMT) data, both for phantoms and small animal in vivo measurements. The technique is based on the recording of tomographic data in multiple spectral regions with different excitation light and on the application of a linear unmixing algorithm for targeting multiple fluorescent probes. Autofluorescence spectra are recorded using an identical reflection geometry as during the FMT acquisitions.

Original languageEnglish
Title of host publicationBiomedical Topical Meeting, BIO 2006
PublisherOptical Society of America
ISBN (Print)1557528071, 9781557528070
StatePublished - 2006
Externally publishedYes
EventBiomedical Topical Meeting, BIO 2006 - Fort Lauderdale, FL, United States
Duration: 19 Mar 200619 Mar 2006

Publication series

NameOptics InfoBase Conference Papers
ISSN (Electronic)2162-2701

Conference

ConferenceBiomedical Topical Meeting, BIO 2006
Country/TerritoryUnited States
CityFort Lauderdale, FL
Period19/03/0619/03/06

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